CRMP2 Rabbit anti-Mouse, Rat, Polyclonal, Invitrogen™

Rabbit Polyclonal Antibody

Brand:  Invitrogen PA3120

Product Code. 11548771

Description

PA3-120 detects TOAD-64 in rat samples. PA3-120 has been successfully used in Western blot, immunoprecipitation and immunohistochemistry (frozen) procedures. By Western blot, this antibody detects an 64 kDa protein representing TOAD-64 in rat samples. The PA3-120 immunogen is a synthetic peptide corresponding to residues Y(499) D G P V F D L T T T P K(511) of TUC-4a (residues 612-624 of TUC-4b).

TOAD-64 is a 64 kDa intracellular neural protein, which belongs to a family of genes that inhibit nerve growth. It also appears to be involved in a role of axon outgrowth. Preliminary results indicate inhibition of TOAD-64 expression poteintiates neurite outgrowth, and may lead to the design of therapies that promote axonal regeneration. Antibodies to TOAD-64 render neurons insensitive to extracellular compounds that inhibit neuron growth. Very few reagents are able to identify newly born neurons as well as antibodies to TOAD-64.

Specifications

• Antigen: CRMP2
• Classification: Polyclonal
• Gene: Dpysl2
• Gene Alias: Turned On After Division 64, DRP2, CRMP-2, DPYL2, Dihydropyrimidinase-related protein 2, Collapsin response mediator protein 2
• Host Species: Rabbit
• Quantity: 100 μL
• Primary or Secondary: Primary
• Target Species: Mouse, Rat
• Product Type: Antibody
• Isotype: IgG

• Applications: Immunocytochemistry, Immunofluorescence, Immunohistochemistry (Frozen), Immunoprecipitation, Western Blot
• Conjugate: Unconjugated
• Gene Accession No.: O08553, P47942
• Gene Symbols: DPYSL2
• Immunogen: Synthetic peptide corresponding to residues Y(499) D G P V F D L T T T P K(511) of TUC-4a (residues 612-624 of TUC-4b).
• Regulatory Status: RUO
• Gene ID (Entrez): 12934, 25416
• Content And Storage: -20° C, Avoid Freeze/Thaw Cycles
• Form: Liquid