Transferrin Monoclonal Antibody (A78-G/A7), Invitrogen™

Mouse Monoclonal Antibody

Brand:  Invitrogen MA513466

Product Code. 11354853

Description

MA5-13466 targets Thomsen-Friedenreich Antigen in immunofluorescence and immohistochemistry (Paraffin) applications and shows reactivity with Human and Rat samples. Staining of formalin-fixed tissues requires boiling tissue section in 10 mM citrate buffer, pH 6.0 for 10-20 minutes followed by cooling at room temperature for 20 minutes. The MA5-13466 immunogen is neuraminidase-treated human red blood cells.

Transferrins (Tf) are an approximately 80kDa blood plasma glycoprotein synthesized by the liver. They are iron binding transport proteins which can bind two Fe(3+) ions in association with the binding of an anion, usually bicarbonate. It is responsible for the transport of iron from sites of absorption and heme degradation to those of storage and utilization. Transferrin is the primary blood iron transport protein and under normal conditions; approximately one-third of total blood transferrin contains bound iron. Measurement of blood transferrin levels can be used as an indicator for blood iron-carrying capacity and abnormalities of iron metabolism such as anaemia, iron overload and haemochromatosis.Serum transferrin may also have a further role in stimulating cell proliferation.

Specifications

• Antigen: Transferrin
• Classification: Monoclonal
• Concentration: 0.2 mg/mL
• Formulation: PBS with 0.2% BSA and 0.09% sodium azide; pH 7.4
• Gene Accession No.: P02787, P12346
• Gene Symbols: Tf
• Immunogen: Neuraminidase-treated human red blood cells
• Quantity: 500 μL
• Primary or Secondary: Primary
• Target Species: Human, Rat
• Product Type: Antibody
• Isotype: IgM κ

• Applications: Immunocytochemistry, Immunohistochemistry (Paraffin)
• Clone: A78-G/A7
• Conjugate: Unconjugated
• Gene: Tf
• Gene Alias: AI266983; beta-1 metal-binding globulin; Cd176; DKFZp781D0156; epididymis secretory sperm binding protein Li 71p; HEL-S-71p; HP; hpx; hypotransferrinemia with hemochromatosis; ICA; Inhibitor of carbonic anhydrase; lactoferrin; liver regeneration-related protein LRRG03; liver transferrin; LOC100146633; PICA; porcine inhibitor of carbonic anhydrase; porcine inhibitor of carbonic anhydrase precursor; PRO1400; PRO1557; PRO2086; Serotransferrin; siderophilin; TF; Tfn; TFQTL1; transferin; Transferrin; transferrin precursor; Trf
• Host Species: Mouse
• Purification Method: Ammonium sulfate precipitation
• Regulatory Status: RUO
• Gene ID (Entrez): 24825, 7018
• Content And Storage: 4° C
• Form: Liquid