SSTR5 Polyclonal Antibody, Invitrogen™

Rabbit Polyclonal Antibody

Brand:  Invitrogen PA534224

Product Code. 15395131

Description

Percent identity with other species by BLAST analysis: Human (100%) Gorilla, Marmoset (94%).

Somatostatin is a multifunctional protein affecting exocrine and endocrine protein secretion, neurotransmission, and neuronal modulation and regulating cell proliferation. All these functions of Somatostatin are executed through a class of GPCR protein family members called somatostatin receptor. Till date, 6 classes of somatostatin receptors have been discovered out of which SSTR5, 364A.A protein, is a receptor subtype expressed predominantly in the pituitary and hypothalamus region of brain. Studies revealed that SSTR5 contains seven transmembrane regions and undergoes homodimerization and also heterodimerizes with SSTR1. Although the specific functions of SSTR5 are still elusive, the studies indicate that it complements SSTR2 regulation of ACTH secretion. Polymorphisms in SSTR5 gene have been observed in patients with acromegaly.

Specifications

• Antigen: SSTR5
• Classification: Polyclonal
• Conjugate: Unconjugated
• Gene: Sstr5
• Gene Alias: Smstr5; Somato; somatostatin receptor; somatostatin receptor 5; Somatostatin receptor subtype 5; somatostatin receptor type 5; SS5R; SS-5-R; SS5-R; sst5; Sstr5
• Host Species: Rabbit
• Purification Method: Antigen affinity chromatography
• Regulatory Status: RUO
• Gene ID (Entrez): 6755
• Content And Storage: Store at 4°C short term. For long term storage, store at -20°C, avoiding freeze/thaw cycles.
• Form: Liquid

• Applications: Immunohistochemistry (Paraffin)
• Concentration: 1 mg/mL
• Formulation: PBS with 0.1% sodium azide
• Gene Accession No.: P35346
• Gene Symbols: Sstr5
• Immunogen: Synthetic 18 amino acid peptide from C-terminus of human SSTR5.
• Quantity: 50 μg
• Primary or Secondary: Primary
• Target Species: Human
• Product Type: Antibody
• Isotype: IgG