SPP1 Polyclonal Antibody, Invitrogen™

SPP1 Antibody, PA5-34579, from Invitrogen™. Species Reactivity: Human, Mouse, Rat; Applications: Immunocytochemistry, Immunofluorescence, Immunohistochemistry, Western Blot.

Overview
Brand: Invitrogen

Manufacturer Part Number: PA5-34579

Polyclonal Antibody, SPP1, host Rabbitisotype IgG

UNSPSC: 12352203

Code: NEW

Additional Details:
Additional Details: Weight: 0.01000kg



Product Code. 15365501

Quantity Price
1 £ 317.0 / 100µg
Estimated Shipment date
from Supplier 19-12-2016
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Description and Specification

Specification

Antigen SPP1
Applications Immunocytochemistry
Applications Immunofluorescence
Applications Immunohistochemistry
Applications Western Blot
Conjugate Unlabeled
Cross Reactivity Human
Cross Reactivity Mouse
Cross Reactivity Rat
Format Purified
Formulation 100μg purified antibody (1mg/mL) in PBS and 0.02% sodium azide
Gene Accession No. P08721, P10451, P10923
Gene Alias SPP1, Secreted phosphoprotein 1, osteopontin, OPN, BNSP, BSPI, ETA-1
Gene Symbols SPP1
Host Species Rabbit
Immunogen An 18 amino acid peptide near the amino terminus of human SPP1
Isotype IgG
Quantity 100μg
Species Reactivity Human, Mouse, Rat
Storage Requirements Store at 2-8°C for up to 3 months. For long term storage store at -20°C
Primary or Secondary Primary
Monoclonal or Polyclonal Polyclonal
Gene ID (Entrez) 20750, 25353, 6696

The secreted protein 1 (SPP1), also known as osteopontin, is a major noncollagenous protein of bone, but is also found in the extracellular matrix of other mineralized tissues and in bodily fluids. In bone, SPP1 is produced by osteoblasts, osteocytes, macrophages, and osteoclasts. SPP1 binds to cells through integrin and non-integrin receptors, as well as the adhesion receptor CD44 in an RGD-independent manner, enabling SPP1 to induce a number of functional effects including macrophage chemotaxis, cytoprotection, and regulation of T helper type 1 cells. SPP1 can regulate biomineralization by inhibiting the formation of hydroxyapatite and the growth of calcium oxalate crystals.
Host Species: Rabbit
Cross Reactivity: Human, Mouse, Rat
Isotype: IgG
Immunogen: An 18 amino acid peptide near the amino terminus of human SPP1
Formulation: 100 ug purified antibody (1mg/mL) in PBS and 0.02% sodium azide
Synonyms: SPP1, Secreted phosphoprotein 1, osteopontin, OPN, BNSP, BSPI, ETA-1
Uniprot Accession: P08721, P10451, P10923
Entrez GeneID: 20750, 25353, 6696
Gene Symbol: SPP1
A suggested positive control is human bladder tissue lysate. PA5-34579 can be used with blocking peptide PEP-1622.