SOX17 Rabbit anti-Human, Marsupial, Mouse, Non-human primate, Rat, Zebrafish, Polyclonal, Invitrogen™

Rabbit Polyclonal Antibody

Brand:  Invitrogen PA523352

Product Code. 13287918

Description

SOX17, also known as transcription factor SOX-17, as the name suggests is a transcription factor or a probable transcriptional activator in the premeiotic germ cells. It belongs to the SRY-related HMG box family of transcription factors with a high-mobility group DNA-binding domain (HMG box), that plays a key role in embryogenesis and binds to the sequences 5′-AACAAT-′3 or 5′-AACAAAG-3′. SOX17 plays an essential role in cardiac mesoderm specification as well as in definitive hematopoiesis, maintaining fetal hematopoietic stem cells, hematopoiesis in the fetal liver and yolk sac. Along with beta-catenin, it is known to cooperate in the regulation of transcription of endodermal genes. Defects in SOX17 are known to cause a severe defects in fetal hematopoiesis. 

Specifications

• Antigen: SOX17
• Classification: Polyclonal
• Conjugate: Unconjugated
• Gene Accession No.: Q9H6I2, Q61473
• Gene Symbols: SOX17
• Immunogen: Synthetic peptide (80 KDERKRLAQQNPDLHNAEL 98) of SOX17 protein.
• Quantity: 100 μg
• Primary or Secondary: Primary
• Target Species: Human, Marsupial, Mouse, Non-human Primate, Rat, Zebrafish
• Product Type: Antibody
• Isotype: IgG

• Applications: Immunohistochemistry (Paraffin), Western Blot
• Concentration: 1 mg/mL
• Gene: SOX17
• Gene Alias: VUR3, SRY-related HMG-box transcription factor SOX17, transcription factor SOX-17
• Host Species: Rabbit
• Purification Method: Antigen affinity chromatography
• Regulatory Status: RUO
• Gene ID (Entrez): 20671, 30544, 312936, 64321
• Content And Storage: Store at 4°C short term. For long term storage, store at -20°C, avoiding freeze/thaw cycles.
• Form: Liquid