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CXCL12 Mouse anti-Human, Clone: 79018, Invitrogen™

Mouse Monoclonal Antibody

Brand:  Invitrogen MA523759

Code : NEW

Additional Details : Weight : 0.00010kg

Product Code. 15523452

  • £340.00 / 500µg

EU Stock 1

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Description

Description

CXCL12, Stromal cell derived factor beta 1 (SDF1) is a 70 amino acid CXC chemokine originally cloned from a bone marrow stromal cell line. This member of the intercrine alpha (chemokine CxC) family is a chemoattractant active on T lymphocytes, monocytes, but not neutrophils. Targeted deletion of SDF1 gene resulted in defects of B cell lymphopoiesis and bone marrow myelopoiesis in mice. SDF1 has been shown to be chemotactic for lymphocytes. In addition, SDF1 was recently reported to be a ligand for CXCR4 (LESTR/fusin) and a co receptor for HIV1 entry into T cells (SDF1 binding to CXCR4 inhibits HIV1 entry).
Specifications

Specifications

CXCL12
Monoclonal
0.5 mg/mL
PBS with 5% trehalose and No Preservative
P48061
Stromal cell-derived factor 1, hSDF-1, C-X-C motif chemokine 12, Intercrine reduced in hepatomas, IRH, hIRH, Pre-B cell growth-stimulating factor, PBSF, CXCL12, SDF1, SDF1A, SDF1B
Mouse
IgG1
500 μg
-20° C, Avoid Freeze/Thaw Cycles
Primary
6387
ELISA, Flow Cytometry, Immunohistochemistry (Paraffin)
79018
Unconjugated
CXCL12
Lyophilized
CXCL12
E. coli-derived recombit human CXCL12/SDF-1 alpha Lys22-Lys89
Protein A/G
RUO
Antibody
Monoclonal
Human
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