ROC1 Polyclonal Antibody, Invitrogen™

ROC1 Antibody, PA5-16282, from Invitrogen™. Species Reactivity: Human, Mouse; Applications: Immunoprecipitation, Western Blot.

Overview
Brand: Invitrogen

Manufacturer Part Number: PA5-16282

ROC1 RABBIT POLYCLONAL ANTIBODY

UNSPSC: 12352203

Code: A0

Additional Details:
Additional Details: Weight: 0.01000kg



Product Code. 11375743

Quantity Price
1 £ 315.0 / 500µL
Estimated Shipment date
from Supplier 09-12-2016
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Description and Specification

Specification

Antigen ROC1
Applications Immunoprecipitation
Applications Western Blot
Conjugate Unlabeled
Cross Reactivity Human
Cross Reactivity Mouse
Format Purified
Formulation 500μL purified antibody (1mg/mL) in PBS with 0.2% BSA and 0.09% sodium azide; pH 7.4
Gene Accession No. P62877, P62878
Gene Alias RING box protein 1, RING finger protein 75, RING-box protein 1, ZYP protein, regulator of cullins 1
Gene Symbols RBX1
Host Species Rabbit
Immunogen A peptide corresponding to amino acid residue 97-108 (CPLDNREWEFQKYGH) from C-terminus of the human ROC1
Isotype IgG
Quantity 500μL
Regulatory Status RUO
Species Reactivity Human, Mouse
Storage Requirements Store at 4° C
Primary or Secondary Primary
Monoclonal or Polyclonal Polyclonal
Gene ID (Entrez) 56438, 9978

ROC1 and ROC2 are the two highly conserved RING finger proteins that are homologous to APC11, a subunit of the anaphase-promoting complex(APC). ROC1 and ROC2 commonly interact with all cullins while APC11 specifically interacts with APC2, a cullin-related APC subunit. ROC1 and APC11 immunocomplexes can catalyze isopeptide ligations to form polyubiquitin chains in an E1- and E2-dependent manner. ROC1 is thought to play a unique role in the ubiquitination reaction by heterodimerizing with cullin1 to catalyze ubiquitin polymerization.
Host Species: Rabbit
Cross Reactivity: Human, Mouse
Isotype: IgG
Immunogen: A peptide corresponding to amino acid residue 97-108 (CPLDNREWEFQKYGH) from C-terminus of the human ROC1
Formulation: 500μL purified antibody (1mg/mL) in PBS with 0.2% BSA and 0.09% sodium azide; pH 7.4
Synonyms: RING box protein 1, RING finger protein 75, RING-box protein 1, ZYP protein, regulator of cullins 1
Uniprot Accession: P62877, P62878
Entrez GeneID: 56438, 9978
Gene Symbol: RBX1
PA5-16282 targets ROC1 in IP and WB applications and shows reactivity with Human and mouse samples. The PA5-16282 immunogen is a peptide corresponding to amino acid residue 97-108 (CPLDNREWEFQKYGH) from C-terminus of the human ROC1.