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ROC1 Polyclonal Antibody, Invitrogen™

ROC1 Antibody, PA5-16282, from Invitrogen™. Species Reactivity: Human, Mouse; Applications: Immunoprecipitation, Western Blot.

Brand:  Invitrogen PA516282

UNSPSC : 12352203

Code : A0

Additional Details : Weight : 0.01000kg

Product Code. 11375743

  • £315.00 / 500┬ÁL


Estimated Shipment
16-06-2017
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Specifications

Description

ROC1 and ROC2 are the two highly conserved RING finger proteins that are homologous to APC11, a subunit of the anaphase-promoting complex(APC). ROC1 and ROC2 commonly interact with all cullins while APC11 specifically interacts with APC2, a cullin-related APC subunit. ROC1 and APC11 immunocomplexes can catalyze isopeptide ligations to form polyubiquitin chains in an E1- and E2-dependent manner. ROC1 is thought to play a unique role in the ubiquitination reaction by heterodimerizing with cullin1 to catalyze ubiquitin polymerization.
Host Species: Rabbit
Cross Reactivity: Human, Mouse
Isotype: IgG
Immunogen: A peptide corresponding to amino acid residue 97-108 (CPLDNREWEFQKYGH) from C-terminus of the human ROC1
Formulation: 500μL purified antibody (1mg/mL) in PBS with 0.2% BSA and 0.09% sodium azide; pH 7.4
Synonyms: RING box protein 1, RING finger protein 75, RING-box protein 1, ZYP protein, regulator of cullins 1
Uniprot Accession: P62877, P62878
Entrez GeneID: 56438, 9978
Gene Symbol: RBX1
PA5-16282 targets ROC1 in IP and WB applications and shows reactivity with Human and mouse samples. The PA5-16282 immunogen is a peptide corresponding to amino acid residue 97-108 (CPLDNREWEFQKYGH) from C-terminus of the human ROC1.
Description & Specifications

Specifications

ROC1
Unlabeled
P62877, P62878
RING box protein 1, RING finger protein 75, RING-box protein 1, ZYP protein, regulator of cullins 1
Rabbit
IgG
RUO
Primary
56438, 9978
Western Blot
500μL purified antibody (1mg/mL) in PBS with 0.2% BSA and 0.09% sodium azide; pH 7.4
Purified
RBX1
A peptide corresponding to amino acid residue 97-108 (CPLDNREWEFQKYGH) from C-terminus of the human ROC1
500μL
Store at 4° C
Polyclonal
Murine