Invitrogen™ RAD3 Polyclonal Antibody

Rabbit Polyclonal Antibody

Brand:  Invitrogen™ PA532174

Product Code. 13466547

Description

Recommended positive controls: Yeast lysate. Predicted reactivity: Yeast (100%). Store product as a concentrated solution. Centrifuge briefly prior to opening the vial.

ATP-dependent DNA helicase involved in excision repair of DNA damaged with UV light, bulky adducts, or cross-linking agents. Necessary for excision of pyrimidine dimers. Also unwinds DNA/RNA duplexes. Plays an essential role in the cell viability. Involved in the maintenance of the fidelity of DNA replication. Acts as component of the general transcription and DNA repair factor IIH (TFIIH) core, which is essential for both basal and activated transcription, and is involved in nucleotide excision repair (NER) of damaged DNA. TFIIH has CTD kinase and DNA-dependent ATPase activity, and is essential for polymerase II transcription in vitro.

Specifications

• Antigen: RAD3
• Classification: Polyclonal
• Conjugate: Unconjugated
• Gene: RAD3
• Gene Alias: DNA repair helicase RAD3; General transcription and DNA repair factor IIH helicase subunit XPD; RAD3; REM1; RNA polymerase II transcription factor B subunit RAD3; TFB subunit RAD3; TFIIH subunit XPD; TFIIH/NER complex ATP-dependent 5'-3' DNA helicase subunit RAD3; YER171W
• Host Species: Rabbit
• Purification Method: Antigen affinity chromatography
• Regulatory Status: RUO
• Gene ID (Entrez): 856918
• Content And Storage: Store at 4°C short term. For long term storage, store at -20°C, avoiding freeze/thaw cycles.
• Form: Liquid

• Applications: Western Blot
• Concentration: 0.9 mg/mL
• Formulation: 0.1M tris glycine with 20% glycerol and 0.01% thimerosal; pH 7
• Gene Accession No.: P06839
• Gene Symbols: RAD3
• Immunogen: Recombinant protein encompassing a sequence within the N-terminus region of Saccharomyces cerevisiae S288c RAD3. The exact sequence is proprietary.
• Quantity: 100 μL
• Primary or Secondary: Primary
• Target Species: Yeast
• Product Type: Antibody
• Isotype: IgG