Invitrogen™ PDHB Polyclonal Antibody

Rabbit Polyclonal Antibody

Brand:  Invitrogen™ PA527989

Product Code. 13422107

Description

Recommended positive controls: A549, H1299, HCT116, mouse heart, rat heart. Predicted reactivity: Mouse (94%), Rat (94%), Zebrafish (85%), Xenopus laevis (84%), Pig (94%), Chicken (85%), Rhesus Monkey (100%), Chimpanzee (100%), Bovine (94%). Store product as a concentrated solution. Centrifuge briefly prior to opening the vial.

PDHB (Pyruvate dehydrogenase E1 component subunit beta, mitochondrial) is also named as PHE1B. The enzyme, which is found in mitochondria, is one of the component enzymes of the pyruvate dehydrogenase multienzyme complex (PDH). It catalyzes the first reaction of an oxidative decarboxylation sequence converting pyruvate to acetyl-CoA and CO(2). Defects in PDHB are the cause of pyruvate dehydrogenase E1-beta deficiency (PDHBD).

Specifications

• Antigen: PDHB
• Classification: Polyclonal
• Conjugate: Unconjugated
• Gene: PDHB
• Gene Alias: 2610103L06Rik; AL024199; C81408; PDHB; PDHBD; PDHE1-B; PHE1B; pyruvate dehydrogenase (lipoamide) beta; pyruvate dehydrogenase E1 component subunit beta, mitochondrial; pyruvate dehydrogenase, E1 beta polypeptide
• Host Species: Rabbit
• Purification Method: Antigen affinity chromatography
• Regulatory Status: RUO
• Gene ID (Entrez): 289950, 5162, 68263
• Content And Storage: Store at 4°C short term. For long term storage, store at -20°C, avoiding freeze/thaw cycles.
• Form: Liquid

• Applications: Immunohistochemistry (Paraffin), Western Blot, Immunocytochemistry
• Concentration: 1 mg/mL
• Formulation: PBS with 1% BSA, 20% glycerol and 0.01% thimerosal; pH 7
• Gene Accession No.: P11177, P49432, Q9D051
• Gene Symbols: PDHB
• Immunogen: Recombinant protein encompassing a sequence within the center region of human Pyruvate Dehydrogenase E1 beta subunit. The exact sequence is proprietary.
• Quantity: 100 μL
• Primary or Secondary: Primary
• Target Species: Human, Mouse, Rat
• Product Type: Antibody
• Isotype: IgG