Invitrogen™ PCDHGB2 Monoclonal Antibody (6E9)

Mouse Monoclonal Antibody

Brand:  Invitrogen™ MA522246

Product Code. 15529092

Description

Peptide Sequence: QICGKQPLCV LDFDTVAENP LNIFYIAVIV QDINDNTPLF KQTKINLKIG ESTKPGTTFP LDPALDSDVG PNSLQRYHLN DNEYFDLAEK QTPDGRKYPE LILKHS.

This gene is a member of the protocadherin gamma gene cluster, one of three related clusters tandemly linked on chromosome five. These gene clusters have an immunoglobulin-like organization, suggesting that a novel mechanism may be involved in their regulation and expression. The gamma gene cluster includes 22 genes divided into 3 subfamilies. Subfamily A contains 12 genes, subfamily B contains 7 genes and 2 pseudogenes, and the more distantly related subfamily C contains 3 genes. The tandem array of 22 large, variable region exons are followed by a constant region, containing 3 exons shared by all genes in the cluster. Each variable region exon encodes the extracellular region, which includes 6 cadherin ectodomains and a transmembrane region. The constant region exons encode the common cytoplasmic region. These neural cadherin-like cell adhesion proteins most likely play a critical role in the establishment and function of specific cell-cell connections in the brain. Alternative splicing has been described for the gamma cluster genes.

Specifications

• Antigen: PCDHGB2
• Classification: Monoclonal
• Concentration: 0.2-1.0 mg/mL
• Formulation: PBS with no preservative; pH 7.4
• Gene Accession No.: Q9Y5G2
• Gene Symbols: PCDHGB2
• Immunogen: PCDHGB2 (NP_061746, 94 a.a. ~ 199 a.a) partial recombinant protein with GST tag. MW of the GST tag alone is 26 KDa.
• Quantity: 100 μg
• Primary or Secondary: Primary
• Target Species: Human
• Product Type: Antibody
• Isotype: IgG2a κ

• Applications: ELISA, Western Blot
• Clone: 6E9
• Conjugate: Unconjugated
• Gene: PCDHGB2
• Gene Alias: 3' RACE product; PCDH-gamma-B2; PCDHGB2; protocadherin gamma B2; protocadherin gamma subfamily B, 2; protocadherin gamma-B2
• Host Species: Mouse
• Purification Method: Affinity Chromatography
• Regulatory Status: RUO
• Gene ID (Entrez): 56103
• Content And Storage: -20°C, Avoid Freeze/Thaw Cycles
• Form: Liquid