POU3F2 Polyclonal Antibody, Invitrogen™
POU3F2 Antibody, PA5-34469, from Invitrogen™. Species Reactivity: Human, Mouse, Rat; Applications: Immunofluorescence, Immunohistochemistry, Western Blot.
Brand: Invitrogen PA534469
Code : NEW
Additional Details : Weight : 0.01000kg
DescriptionPOU3F2, also commonly known as brain-2, is a member of a family of POU domain genes expressed in mouse brain and is thought to be involved in the development of the neocortex and establishment of neural cell lineage. Recent studies suggest that POU3F2 may be involved with the development of neurodegenerative diseases as well as tumor development and proliferation. Along with the neural-lineage-specific transcription factors ASCL1 and MYT1L, POU3F2 can convert fibroblasts to functional neurons in vitro, a form of artificial stem cells termed induced neuronal (iN) cells, suggesting that these cells may be useful in the treatment of neurodegenerative diseases.
Host Species: Rabbit
Cross Reactivity: Human, Mouse, Rat
Immunogen: An 18 amino acid peptide near the carboxy terminus of human POU3F2
Formulation: 100 ug purified antibody (1mg/mL) in PBS and 0.02% sodium azide
Synonyms: POU3F2, POU domain class 3 transcription factor 2, POUF3, brain-2, BRN2, brn-2, octamer-binding protein 7, OCT7, OCT-7, OTF7, OTF-7, N-Oct3
Uniprot Accession: P20265, P31360, P56222
Entrez GeneID: 18992, 29588, 5454
Gene Symbol: POU3F2
A suggested positive control is NIH-3T3 cell lysate. PA5-34469 can be used with blocking peptide PEP-1511.
|P20265, P31360, P56222|
|POU3F2, POU domain class 3 transcription factor 2, POUF3, brain-2, BRN2, brn-2, octamer-binding protein 7, OCT7, OCT-7, OTF7, OTF-7, N-Oct3|
|Store at 2-8°C for up to 3 months. For long term storage store at -20°C|
|100μg purified antibody (1mg/mL) in PBS and 0.02% sodium azide|
|An 18 amino acid peptide near the carboxy terminus of human POU3F2|
|18992, 29588, 5454|