Invitrogen™ PML Polyclonal Antibody

Rabbit Polyclonal Antibody

Brand:  Invitrogen™ PA529614

Product Code. 13423807

Description

Recommended positive controls: A549, HeLa, HepG2, HCT116. Predicted reactivity: Rhesus Monkey (98%), Chimpanzee (100%), Bovine (84%). Store product as a concentrated solution. Centrifuge briefly prior to opening the vial.

The protein encoded by this gene is one of two human homologs of Saccharomyces cerevisiae Rad23, a protein involved in nucleotide excision repair (NER). This protein was shown to interact with, and elevate the nucleotide excision activity of 3-methyladenine-DNA glycosylase (MPG), which suggested a role in DNA damage recognition in base excision repair. This protein contains an N-terminal ubiquitin-like domain, which was reported to interact with 26S proteasome, as well as with ubiquitin protein ligase E6AP, and thus suggests that this protein may be involved in the ubiquitin mediated proteolytic pathway in cells.

Specifications

• Antigen: PML
• Classification: Polyclonal
• Conjugate: Unconjugated
• Gene: PML
• Gene Alias: 1200009E24Rik; AI661194; MYL; Pml; PML/RARA fusion; pml1; PP8675; probable transcription factor PML; promyelocytic leukemia; promyelocytic leukemia protein; promyelocytic leukemia, inducer of; protein PML; RGD1562602; RING finger protein 71; RNF71; TRIM19; tripartite motif protein TRIM19; tripartite motif-containing protein 19
• Host Species: Rabbit
• Purification Method: Antigen affinity chromatography
• Regulatory Status: RUO
• Gene ID (Entrez): 5371
• Content And Storage: Store at 4°C short term. For long term storage, store at -20°C, avoiding freeze/thaw cycles.
• Form: Liquid

• Applications: Immunoprecipitation, Western Blot
• Concentration: 1 mg/mL
• Formulation: 0.1M tris glycine with 20% glycerol and 0.01% thimerosal; pH 7
• Gene Accession No.: P29590
• Gene Symbols: PML
• Immunogen: Recombinant protein encompassing a sequence within the N-terminus region of human PML. The exact sequence is proprietary.
• Quantity: 100 μL
• Primary or Secondary: Primary
• Target Species: Human
• Product Type: Antibody
• Isotype: IgG