missing translation for 'onlineSavingsMsg'
Learn More
  1. Home
  2. Products
  3. Antibodies
  4. Primary Antibodies
  5. All Primary Antibodies
  6. PI3-Kinase C2β Mouse anti-Human, Unlabeled, Clone: 22, BD

PI3-Kinase C2β Mouse anti-Human, Unlabeled, Clone: 22, BD

Product Code. 15835889
Change view
Click to view available options
Quantity:
150 μg
50 μg
Unit Size:
1 set
2 product options available for selection
Product selection table with 2 available options. Use arrow keys to navigate and Enter or Space to select.
Product Code. Quantity unitSize
15835889 50 μg 1 set
15845889 150 μg 1 set
Use arrow keys to navigate between rows. Press Enter or Space to select a product option. 2 options available.
2 options
This item is not returnable. View return policy
Product Code. 15835889 Supplier BD Biosciences Supplier No. 611342

Please to purchase this item. Need a web account? Register with us today!

This item is not returnable. View return policy

Description

Mouse Monoclonal Antibody

Phosphatidylinositol (PtdIns) (3) kinase phosphorylates the D-3 position of the inositolring of PtdIns, producing PtdIns(3)P, PtdIns(3,4)P2, and PtdIns(3,4,5)P3. PI3-kinase is a heterodimer of an 85kDa regulatory subunit (p85) and a 110kDa catalytic subunit (p110). However, it is only one member of a larger family of proteins with similarity to the p110 subunit. These different PI3-kinase isoforms have been divided into three classes. Class I consists of p110α and p110-» which bind the p85 subunit and associate with receptor tyrosine kinases. Class II includes 68D and cpk from Drosophila, p170 and cpk-m from mouse, and C2α, C2-» (HsC2), and C2γ from human. These proteins phosphorylate PtdIns and PtdIns(4)P, but not PtdIns(4,5)P2, and each contain a C-terminal C2 domain that may negatively regulate the catalytic domain. Class III members only phosphorylate PtdIns to PtdIns(3)P and include the S. cerevisiae Vps34p and its human homologs. In humans, the class II PI3-kinases C2α and C2-» have similar catalytic, PI kinase, and C2 domains. However they differ in their N-terminal regions. In addition, C2β has no cation specificity, while C2α prefers Mg2+-ATP for optimal phosphorylation.

Host Species: Mouse
Clone: 22
Isotype: IgG1
Species Reactivity: Human
Immunogen: Human PI3-Kinase C2β aa. 16-209
Formula Weight [Chemical]: 165kDa

Immunofluorescence, Western Blotting

TRUSTED_SUSTAINABILITY

Specifications

Antigen PI3-Kinase C2β
Applications Western Blot
Classification Monoclonal
Clone 22
Concentration 250μg/mL
Conjugate Unconjugated
Formulation Aqueous buffered solution containing BSA, glycerol, and ≤0.09% sodium azide.
Host Species Mouse
Immunogen Human PI3-Kinase C2β aa. 16-209
Purification Method Affinity Purified
Quantity 50 μg
Regulatory Status RUO
Research Discipline Cell Biology
Primary or Secondary Primary
Target Species Human
Content And Storage Store undiluted at -20°C.
Isotype IgG1
Show More Show Less

For Research Use Only.

Product Title
Select an issue

By clicking Submit, you acknowledge that you may be contacted by Fisher Scientific in regards to the feedback you have provided in this form. We will not share your information for any other purposes. All contact information provided shall also be maintained in accordance with our Privacy Policy.