Invitrogen™ PMM2 Polyclonal Antibody

Rabbit Polyclonal Antibody

Brand:  Invitrogen™ PA522323

Product Code. 13229778

Description

Recommended positive controls: 293T, HeLa, HepG2. Predicted reactivity: Mouse (93%), Rat (95%), Chicken (86%), Rhesus Monkey (98%), Bovine (93%). Store product as a concentrated solution. Centrifuge briefly prior to opening the vial.

The protein encoded by this gene catalyzes the isomerization of mannose 6-phosphate to mannose 1-phosphate, which is a precursor to GDP-mannose necessary for the synthesis of dolichol-P-oligosaccharides. Mutations in this gene have been shown to cause defects in glycoprotein biosynthesis, which manifests as carbohydrate-deficient glycoprotein syndrome type I.

Specifications

• Antigen: PMM2
• Classification: Polyclonal
• Conjugate: Unconjugated
• Gene: PMM2
• Gene Alias: AI585868; C86848; CDG1; CDG1a; CDGS; mannose-6-phosphate isomerase; phosphomannomutase 2; phosphomannose isomerase 1; PMI; PMI1; PMM 2; Pmm2
• Host Species: Rabbit
• Purification Method: Antigen affinity chromatography
• Regulatory Status: RUO
• Gene ID (Entrez): 5373
• Content And Storage: Store at 4°C short term. For long term storage, store at -20°C, avoiding freeze/thaw cycles.
• Form: Liquid

• Applications: Immunohistochemistry (Paraffin), Western Blot
• Concentration: 0.24 mg/mL
• Formulation: 0.1M tris glycine with 20% glycerol and 0.01% thimerosal; pH 7
• Gene Accession No.: O15305
• Gene Symbols: PMM2
• Immunogen: Recombinant protein encompassing a sequence within the center region of human PMM2. The exact sequence is proprietary.
• Quantity: 100 μL
• Primary or Secondary: Primary
• Target Species: Human
• Product Type: Antibody
• Isotype: IgG