Phospho-nNOS (Ser852) Polyclonal Antibody, Invitrogen™

Product Code.	Quantity	unitSize
15525231	100 μg	100µg

Product Code. 15525231 Supplier Invitrogen Supplier No. PA538305

Description

Rabbit Polyclonal Antibody

NOS activity requires homodimerization as well as three cosubstrates (L-arginine, NADPH and O2) and five cofactors or prosthetic groups (FAD, FMN, calmodulin, tetrahydrobiopterin and heme). Several distinct NOS isoforms have been described and been shown to represent the products of three distinct genes. These include two constitutive Ca2+/CaM-dependent forms of NOS, including NOS1 (also designated ncNOS) whose activity was first identified in neurons, and NOS3 (also designated ecNOS), first identified in endothelial cells.

Specifications

• Antigen: Phospho-nNOS (Ser852)
• Applications: Immunocytochemistry, Immunofluorescence, Immunohistochemistry (Paraffin), Western Blot
• Classification: Polyclonal
• Concentration: 1 mg/mL
• Conjugate: Unconjugated
• Formulation: Dulbecco′s PBS with 150mM NaCl, 50% glycerol and 0.02% sodium azide; pH 7.4
• Gene: NOS1
• Gene Accession No.: P29475, Q9Z0J4, P29476
• Gene Alias: Nitric oxide synthase, brain, Constitutive NOS, NC-NOS, NOS type I, Neuronal NOS, N-NOS, nNOS, Peptidyl-cysteine S-nitrosylase NOS1, bNOS, NOS1
• Gene Symbols: NOS1
• Host Species: Rabbit
• Immunogen: A synthetic phosphopeptide derived from human n-NOS around the phosphorylation site of Ser847 (F-N-SP-V-S)
• Purification Method: Antigen affinity chromatography
• Quantity: 100 μg
• Regulatory Status: RUO
• Primary or Secondary: Primary
• Gene ID (Entrez): 18125, 24598, 4842
• Target Species: Human, Mouse, Rat
• Content And Storage: -20°C
• Product Type: Antibody
• Form: Liquid
• Isotype: IgG