anti-Phospho-Doublecortin/DCX pSer334 Polyclonal, Invitrogen™

Phospho-Doublecortin/DCX pSer334 Polyclonal antibody A16585 from Thermo Scientific™ Pierce™ specifically detects Phospho-Doublecortin/DCX pSer334 in Human samples, and it is validated for WB, IF and IP

Brand:  Invitrogen A16585

Product Code. 15374036

Description

In the developing cortex, cortical neurons must migrate over long distances to reach the site of their final differentiation. The protein encoded by this gene is a cytoplasmic protein which appears to direct neuronal migration by regulating the organization and stability of microtubules. The encoded protein contains two doublecortin domains, which bind microtubules. In addition, the encoded protein interacts with LIS1, the regulatory gamma subunit of platelet activating factor acetylhydrolase, and this interaction is important to proper microtubule function in the developing cortex. Mutations in this gene are a cause of X-linked lissencephaly. Multiple transcript variants encoding at least three different isoforms have been found for this gene.

A16585 detects Phospho-Doublecortin/DCX pSer334 in Human samples. A16585 has been successfully used in WB, IF and IP procedures. The immunogen for A16585 is a synthetic phosphopeptide corresponding to residues surrounding Ser334 of doublecortin.

Applications:

Immunofluorescence, Immunoprecipitation, Western Blotting

Specifications

• Antigen: Phospho-Doublecortin/DCX pSer334
• Conjugate: Unconjugated
• Host Species: Rabbit
• Primary or Secondary: Primary
• Target Species: Human
• Form: Purified

• Classification: Polyclonal
• Gene Accession No.: O43602
• Immunogen: A synthetic phosphopeptide corresponding to residues surrounding Ser334 of doublecortin
• Gene ID (Entrez): 1641
• Content And Storage: Store at -20°C
• Isotype: IgG