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anti-Phospho-Doublecortin/DCX pSer334 Polyclonal, Invitrogen™

Product Code. 15374036
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Conjugate:
Unconjugated
Unit Size:
100µL
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15374036 Unconjugated 100µL
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Product Code. 15374036 Supplier Invitrogen Supplier No. A16585

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Description

Phospho-Doublecortin/DCX pSer334 Polyclonal antibody A16585 from Thermo Scientific™ Pierce™ specifically detects Phospho-Doublecortin/DCX pSer334 in Human samples, and it is validated for WB, IF and IP

In the developing cortex, cortical neurons must migrate over long distances to reach the site of their final differentiation. The protein encoded by this gene is a cytoplasmic protein which appears to direct neuronal migration by regulating the organization and stability of microtubules. The encoded protein contains two doublecortin domains, which bind microtubules. In addition, the encoded protein interacts with LIS1, the regulatory gamma subunit of platelet activating factor acetylhydrolase, and this interaction is important to proper microtubule function in the developing cortex. Mutations in this gene are a cause of X-linked lissencephaly. Multiple transcript variants encoding at least three different isoforms have been found for this gene.

A16585 detects Phospho-Doublecortin/DCX pSer334 in Human samples. A16585 has been successfully used in WB, IF and IP procedures. The immunogen for A16585 is a synthetic phosphopeptide corresponding to residues surrounding Ser334 of doublecortin.

Applications:

Immunofluorescence, Immunoprecipitation, Western Blotting

TRUSTED_SUSTAINABILITY

Specifications

Antigen Phospho-Doublecortin/DCX pSer334
Classification Polyclonal
Conjugate Unconjugated
Gene Accession No. O43602
Host Species Rabbit
Immunogen A synthetic phosphopeptide corresponding to residues surrounding Ser334 of doublecortin
Primary or Secondary Primary
Gene ID (Entrez) 1641
Target Species Human
Content And Storage Store at -20°C
Form Purified
Isotype IgG
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