Invitrogen™ Phospho-CENPA (Ser7) Polyclonal Antibody

Rabbit Polyclonal Antibody

Brand:  Invitrogen™ PA517195

Product Code. 11586011

Description

It is not recommended to aliquot this antibody. This antibody is not cross-reactive with other histone proteins, including Histone H3.

Centromeres are the differentiated chromosomal domains that specify the mitotic behavior of chromosomes. CENPA encodes a centromere protein which contains a histone H3 related histone fold domain that is required for targeting to the centromere. CENPA is proposed to be a component of a modified nucleosome or nucleosome-like structure in which it replaces 1 or both copies of conventional histone H3 in the (H3-H4)2 tetrameric core of the nucleosome particle.

Specifications

• Antigen: Phospho-CENPA (Ser7)
• Classification: Polyclonal
• Conjugate: Unconjugated
• Gene: Cenpa
• Gene Alias: CenH3; CENP A; CENPA; CENP-A; Centromere autoantigen A; centromere protein A; centromere protein A, 17kDa; centromere-specific histone; ggCENP-A; histone H3-like centromeric protein A; RGD1563607
• Host Species: Rabbit
• Purification Method: Antigen Affinity Chromatography
• Regulatory Status: RUO
• Gene ID (Entrez): 1058
• Content And Storage: -20°C
• Form: Liquid

• Applications: Immunoprecipitation, Western Blot, Immunocytochemistry
• Concentration: 26 μg/mL
• Formulation: 0.01M HEPES with 100μg/mL BSA, 50% glycerol, 0.15M NaCl and no preservative; pH 7.5
• Gene Accession No.: P49450
• Gene Symbols: Cenpa
• Immunogen: Synthetic phosphopeptide corresponding to residues surrounding pSer7 of human CENP-A protein.
• Quantity: 100 μL
• Primary or Secondary: Primary
• Target Species: Human
• Product Type: Antibody
• Isotype: IgG