Phospho-CCR5 (Ser349) Polyclonal Antibody, Invitrogen™

Rabbit Polyclonal Antibody

Brand:  Invitrogen PA538081

Product Code. 15525011

Description

Receptors for the CC chemokine family include CCR1, CCR2A, CCR3, CCR4, CCR5 and the Duffy blood group antigen. The CC receptors are important in the function of T cell chemotaxis and migration of phagocytic cells to sites of inflammation. The HIV receptor is composed of two molecules, the CD4 binding receptor and a co receptor. The chemokine receptor CCR5 is one of the co receptors used by primary isolates of HIV1. Extracellular domains of CCR5 are important for HIV entry into the target cells.

Specifications

• Antigen: Phospho-CCR5 (Ser349)
• Classification: Polyclonal
• Conjugate: Unconjugated
• Gene: CCR5
• Gene Alias: C-C CKR-5, C-C chemokine receptor type 5, CC-CKR-5, CCR-5, CD195 antigen, CHEMR13, CKR5, CMKBR5, HIV-1 fusion co-receptor, MIP-1 alpha receptor
• Host Species: Rabbit
• Purification Method: Antigen affinity chromatography
• Regulatory Status: RUO
• Gene ID (Entrez): 1234
• Content And Storage: -20°C
• Form: Liquid

• Applications: Western Blot
• Concentration: 1 mg/mL
• Formulation: Dulbecco′s PBS with 150mM NaCl, 50% glycerol and 0.02% sodium azide; pH 7.4
• Gene Accession No.: P51681
• Gene Symbols: CCR5
• Immunogen: A synthetic phosphopeptide derived from human CCR5 around the phosphorylation site of Ser349 (E-I-SP-V-G)
• Quantity: 100 μg
• Primary or Secondary: Primary
• Target Species: Human
• Product Type: Antibody
• Isotype: IgG