Prohibitin Monoclonal Antibody (5H7), Invitrogen™

Mouse Monoclonal Antibody

Brand:  Invitrogen MA515899

Product Code. 12817922

Description

MA5-15899 targets PHB in indirect ELISA, FACS, ICC, IHC, IF and WB applications and shows reactivity with Human, mouse, Non-human primate, and Rat samples. The MA5-15899 immunogen is purified recombinant fragment of human PHB expressed in E. Coli. . MA5-15899 detects PHB which has a predicted molecular weight of approximately 30kDa.

Prohibitin is from an evolutionarily conserved gene that is ubiquitously expressed. It is thought to be a negative regulator of cell proliferation and may be a tumor suppressor. Mutations in PHB have been linked to sporadic breast cancer. Prohibitin is expressed as two transcripts with varying lengths of 3' untranslated region. The longer transcript is present at higher levels in proliferating tissues and cells, suggesting that this longer 3' untranslated region may function as a trans-acting regulatory RNA.

Specifications

• Antigen: Prohibitin
• Classification: Monoclonal
• Concentration: Conc. Not Determined
• Formulation: ascites with 0.03% sodium azide
• Gene Accession No.: P35232, P67778, P67779
• Gene Symbols: PHB
• Immunogen: Purified recombinant fragment of human PHB expressed in E. Coli.
• Regulatory Status: RUO
• Gene ID (Entrez): 18673, 25344, 5245
• Content And Storage: Store at 4°C short term. For long term storage, store at -20°C, avoiding freeze/thaw cycles.
• Form: Liquid

• Applications: ELISA, Flow Cytometry, Immunocytochemistry, Immunohistochemistry, Western Blot
• Clone: 5H7
• Conjugate: Unconjugated
• Gene: PHB
• Gene Alias: BAP 32; Bap32; B-cell receptor-associated protein 32; epididymis luminal protein 215; epididymis secretory sperm binding protein Li 54e; fa18f07; fb09f05; HEL-215; HEL-S-54e; OTTHUMP00000165765; OTTHUMP00000165766; OTTHUMP00000220103; OTTHUMP00000220170; OTTHUMP00000220171; PHB; phb protein; PHB1; Prohibitin; sr:nyz128; wu:fa18f07; wu:fb09f05
• Host Species: Mouse
• Quantity: 100 μL
• Primary or Secondary: Primary
• Target Species: Human, Mouse, Non-human Primate, Rat
• Product Type: Antibody
• Isotype: IgG1