Invitrogen™ PDE3B Monoclonal Antibody (4A4)

Mouse Monoclonal Antibody

Brand:  Invitrogen™ MA519555

Product Code. 15538822

Description

Peptide Sequence: LTPFPGFYPC SEIEDPAEKG DRKLNKGLNR NSLPTPQLRR SSGTSGLLPV EQSSRWDRNN GKRPHQEFGI SSQGCYLNGP FNSNLLTIPK QRSSSVSLTH.

Cyclic nucleotide phosphodiesterase with a dual-specificity for the second messengers cAMP and cGMP, which are key regulators of many important physiological processes. May play a role in fat metabolism. Regulates cAMP binding of RAPGEF3. Through simultaneous binding to RAPGEF3 and PIK3R6 assembles a signaling complex in which the PI3K gamma complex is activated by RAPGEF3 and which is involved in angiogenesis.

Specifications

• Antigen: PDE3B
• Classification: Monoclonal
• Concentration: 0.4 mg/mL
• Formulation: PBS with no preservative; pH 7.4
• Gene Accession No.: Q13370
• Gene Symbols: PDE3B
• Immunogen: PDE3B (NP_000913, 401 a.a. ~ 500 a.a) partial recombinant protein with GST tag. MW of the GST tag alone is 26 KDa.
• Quantity: 100 μg
• Primary or Secondary: Primary
• Target Species: Human
• Product Type: Antibody
• Isotype: IgG2a κ

• Applications: ELISA, Western Blot
• Clone: 4A4
• Conjugate: Unconjugated
• Gene: PDE3B
• Gene Alias: 9830102A01Rik; AI847709; CGIP1; CGI-PDE B; CGIPDE1; cGMP-inhibited 3',5'-cyclic phosphodiesterase B; cGMP-inhibited 3',5'-cyclic phosphodiesterase B; LOW QUALITY PROTEIN: cGMP-inhibited 3',5'-cyclic phosphodiesterase B; cyclic GMP-inhibited phosphodiesterase B; cyclic nucleotide phosphodiesterase; HcGIP1; LOW QUALITY PROTEIN: cGMP-inhibited 3',5'-cyclic phosphodiesterase B; PDE3B; phosphodiesterase 3B; phosphodiesterase 3B cGMP inhibited; phosphodiesterase 3B, cGMP-inhibited
• Host Species: Mouse
• Purification Method: Affinity chromatography
• Regulatory Status: RUO
• Gene ID (Entrez): 5140
• Content And Storage: -20°C, Avoid Freeze/Thaw Cycles
• Form: Liquid