Invitrogen™ PAR6 Polyclonal Antibody

Rabbit Polyclonal Antibody

Brand:  Invitrogen™ PA519770

Product Code. 11397703

Description

PA5-19770 targets PAR6 in IF and WB applications and shows reactivity with Human samples. The PA5-19770 immunogen is synthetic peptide conjugated to KLH derived from within residues 300 to the C-terminus of Human PAR6. PA5-19770 detects PAR6 which has a predicted molecular weight of approximately 37 kDa.

This gene is a member of the PAR6 family and encodes a protein with a PSD95/Discs-large/ZO1 domain and a semi-Cdc42/Rac interactive binding domain. This cell membrane protein is involved in asymmetrical cell division and cell polarization processes as a member of a multi-protein complex. The protein also has a role in the epithelial-to-mesenchymal transition that characterizes the invasive phenotype associated with metastatic carcinomas. Alternate transcriptional splice variants, encoding different isoforms, have been characterized.

Specifications

• Antigen: PAR6
• Classification: Polyclonal
• Conjugate: Unconjugated
• Gene: PARD6A
• Gene Alias: 0710008C04Rik; 2610010A15Rik; PAR6; Par-6; par-6 (partitioning defective 6,) homolog alpha; PAR-6 alpha; par-6 family cell polarity regulator alpha; par-6 partitioning defective 6 homolog alpha; PAR6A; PAR-6A; PAR6alpha; PAR6C; Pard6a; Partitioning defective 6 homolog alpha; partitioning defective protein 6A; partitioning defective-6 homolog alpha; partitioning-defective protein 6; similar to Partitioning defective-6 homolog alpha (PAR-6 alpha) (PAR-6A) (PAR-6) (PAR6C) (Tax interaction protein 40) (TIP-40); tax interaction protein 40; TAX40; Tax-interacting protein 40; Tip-40
• Host Species: Rabbit
• Purification Method: Antigen affinity chromatography
• Regulatory Status: RUO
• Gene ID (Entrez): 50855
• Content And Storage: Store at 4°C short term. For long term storage, store at -20°C, avoiding freeze/thaw cycles.
• Form: Liquid

• Applications: Western Blot, Immunocytochemistry
• Concentration: 1 mg/mL
• Formulation: PBS with 0.02% sodium azide; pH 7.4
• Gene Accession No.: Q9NPB6
• Gene Symbols: PARD6A
• Immunogen: Synthetic peptide conjugated to KLH derived from within residues 300 to the C-terminus of Human PAR6.
• Quantity: 100 μg
• Primary or Secondary: Primary
• Target Species: Human
• Product Type: Antibody
• Isotype: IgG