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Pannexin 1 Rabbit anti-Mouse, Rat, Polyclonal, Invitrogen™
Rabbit Polyclonal Antibody
Brand: Invitrogen 488000
Code : 50
Additional Details : Weight : 0.50000kg
Description
The pannexin gene family encodes a second class of putative gap junction proteins and are highly conserved in invertebrates and mammals. Pannexins (Panx) are four-pass transmembrane proteins that oligomerize to form large pore ion and metabolite-permeable channels. Pannexin-1 (PANX1) and Pannexin-3 are closely related, while Pannexin-2 is a more distant relation. PANX1 is a transmembrane protein that forms a mechanosensitive ATP-permeable channel between adjacent cells and in the endoplasmic reticulum. PANX1 may play a role as a Ca2+ -leak channel to regulate ER Ca2+ homeostasis and regulates neural stem and progenitor cell proliferation.Specifications
Pannexin 1 | |
Polyclonal | |
Unconjugated | |
Q9JIP4, P60570 | |
Panx1 | |
Synthetic peptide derived from the internal region of the mouse Pannexin 1 protein (AccessionNo. NP_062355), which is identical to rat and human sequence. | |
100 μg | |
Primary | |
Mouse, Rat | |
Antibody | |
IgG |
Immunohistochemistry, Western Blot | |
0.25 mg/mL | |
Panx1 | |
PANX1, Pannexin 1, Pannexin-1, PX1, MRS1, UNQ2529, UNQ2529/PRO6028 | |
Rabbit | |
Antigen affinity chromatography | |
RUO | |
315435, 55991 | |
-20°C | |
Liquid |