Pannexin 1 Rabbit anti-Mouse, Rat, Polyclonal, Invitrogen™

Rabbit Polyclonal Antibody

Brand:  Invitrogen 488000

Product Code. 10347883

Description

The pannexin gene family encodes a second class of putative gap junction proteins and are highly conserved in invertebrates and mammals. Pannexins (Panx) are four-pass transmembrane proteins that oligomerize to form large pore ion and metabolite-permeable channels. Pannexin-1 (PANX1) and Pannexin-3 are closely related, while Pannexin-2 is a more distant relation. PANX1 is a transmembrane protein that forms a mechanosensitive ATP-permeable channel between adjacent cells and in the endoplasmic reticulum. PANX1 may play a role as a Ca2+ -leak channel to regulate ER Ca2+ homeostasis and regulates neural stem and progenitor cell proliferation.

Specifications

• Antigen: Pannexin 1
• Classification: Polyclonal
• Conjugate: Unconjugated
• Gene Accession No.: Q9JIP4, P60570
• Gene Symbols: Panx1
• Immunogen: Synthetic peptide derived from the internal region of the mouse Pannexin 1 protein (AccessionNo. NP_062355), which is identical to rat and human sequence.
• Quantity: 100 μg
• Primary or Secondary: Primary
• Target Species: Mouse, Rat
• Product Type: Antibody
• Isotype: IgG

• Applications: Immunohistochemistry, Western Blot
• Concentration: 0.25 mg/mL
• Gene: Panx1
• Gene Alias: PANX1, Pannexin 1, Pannexin-1, PX1, MRS1, UNQ2529, UNQ2529/PRO6028
• Host Species: Rabbit
• Purification Method: Antigen affinity chromatography
• Regulatory Status: RUO
• Gene ID (Entrez): 315435, 55991
• Content And Storage: -20°C
• Form: Liquid