P2X3 Rabbit anti-Human, Polyclonal, Invitrogen™

Rabbit Polyclonal Antibody

Brand:  Invitrogen PA530894

Product Code. 13465397

Description

PA5-30894 targets P2X3 in IF, IHC (P), and WB applications and shows reactivity with Human samples. The PA5-30894 immunogen is recombit fragment corresponding to a region within amino acids 136 and 395 of Human P2X3. Store product as a concentrated solution. Centrifuge briefly prior to opening the vial. For short-term storage (1-2 weeks), product can be stored at 4°C. For long-term storage, aliquot and store product at -20° C or below, avioiding multiple freeze-thaw cycles.

The product of this gene belongs to the family of purinoceptors for ATP. This receptor functions as a ligand-gated ion channel and may transduce ATP-evoked nociceptor activation. Mouse studies suggest that this receptor is important for peripheral pain responses, and also participates in pathways controlling urinary bladder volume reflexes. It is possible that the development of selective antagonists for this receptor may have a therapeutic potential in pain relief and in the treatment of disorders of urine storage.

Specifications

• Antigen: P2X3
• Classification: Polyclonal
• Conjugate: Unconjugated
• Gene Accession No.: P56373
• Gene Symbols: P2RX3
• Immunogen: Recombit fragment corresponding to a region within amino acids 136 and 395 of Human P2X3
• Quantity: 100 μL
• Primary or Secondary: Primary
• Target Species: Human
• Product Type: Antibody
• Isotype: IgG

• Applications: Immunocytochemistry, Immunofluorescence, Immunohistochemistry (Paraffin), Western Blot
• Concentration: 1 mg/mL
• Gene: P2RX3
• Gene Alias: P2X3, ATP receptor, P2X purinoceptor 3, P2X receptor, subunit 3, purinergic receptor P2X3, purinoceptor P2X3, p2xr3
• Host Species: Rabbit
• Purification Method: Antigen affinity chromatography
• Regulatory Status: RUO
• Gene ID (Entrez): 5024
• Content And Storage: Store at 4°C short term. For long term storage, store at -20°C, avoiding freeze/thaw cycles.
• Form: Liquid