NUMB Polyclonal Antibody, Invitrogen™
NUMB Antibody, PA1-16831, from Invitrogen™. Species Reactivity: Chicken, Human, Mouse; Applications: Immunocytochemistry, Immunofluorescence, Western Blot.
Brand: Invitrogen PA116831
Code : LD
Additional Details : Weight : 0.01000kg
DescriptionNumb is an evolutionarily conserved membrane-associated protein. It exists in four isoforms that differ in two functional domains: a phosphotyrosine-binding (PTB) domain and a proline-rich region (PRR). It plays a role in the control of cell fate decisions during development and antagonizes the actions of Notch. Numb proteins appear to control the self-renewal of all neural progenitor cells and could possibly play similar roles in stem-cell maintenance in other tissues.
Host Species: Rabbit
Cross Reactivity: Chicken, Human, Mouse
Immunogen: A synthetic peptide made to a C-terminal region of the murine numb protein sequence (between residues 600-653).
Formulation: 100μL purified antibody (3.5mg/mL) in tris glycine with 0.15M NaCl and 0.05% sodium azide
Synonyms: Protein S171
Uniprot Accession: P49757, Q9QZS3
Entrez GeneID: 18222, 395639, 8650
Gene Symbol: NUMB
The target sequence has 90% sequence homology with rat.
|avoiding freeze/thaw cycles.|
|100μL purified antibody (3.5mg/mL) in tris glycine with 0.15M NaCl and 0.05% sodium azide|
|A synthetic peptide made to a C-terminal region of the murine numb protein sequence (between residues 600-653).|
|18222, 395639, 8650|