NUMB Polyclonal Antibody, Invitrogen™

NUMB Antibody, PA1-16831, from Invitrogen™. Species Reactivity: Chicken, Human, Mouse; Applications: Immunocytochemistry, Immunofluorescence, Western Blot.

Overview
Brand: Invitrogen

Manufacturer Part Number: PA1-16831

NUMB

UNSPSC: 12352203

Code: LD

Additional Details:
Additional Details: Weight: 0.01000kg



Product Code. 11525403

Quantity Price
1 £ 294.0 / 100µL
Estimated Shipment date
from Supplier 04-01-2017
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Description and Specification

Specification

Antigen NUMB
Applications Immunocytochemistry
Applications Immunofluorescence
Applications Western Blot
Conjugate Unlabeled
Cross Reactivity Chicken
Cross Reactivity Human
Cross Reactivity Mouse
Format Purified
Formulation 100μL purified antibody (3.5mg/mL) in tris glycine with 0.15M NaCl and 0.05% sodium azide
Gene Accession No. P49757, Q9QZS3
Gene Alias Protein S171
Gene Symbols NUMB
Host Species Rabbit
Immunogen A synthetic peptide made to a C-terminal region of the murine numb protein sequence (between residues 600-653).
Isotype IgG
Quantity 100μL
Species Reactivity Chicken, Human, Mouse
Storage Requirements avoiding freeze/thaw cycles.
Primary or Secondary Primary
Monoclonal or Polyclonal Polyclonal
Gene ID (Entrez) 18222, 395639, 8650

Numb is an evolutionarily conserved membrane-associated protein. It exists in four isoforms that differ in two functional domains: a phosphotyrosine-binding (PTB) domain and a proline-rich region (PRR). It plays a role in the control of cell fate decisions during development and antagonizes the actions of Notch. Numb proteins appear to control the self-renewal of all neural progenitor cells and could possibly play similar roles in stem-cell maintenance in other tissues.
Host Species: Rabbit
Cross Reactivity: Chicken, Human, Mouse
Isotype: IgG
Immunogen: A synthetic peptide made to a C-terminal region of the murine numb protein sequence (between residues 600-653).
Formulation: 100μL purified antibody (3.5mg/mL) in tris glycine with 0.15M NaCl and 0.05% sodium azide
Synonyms: Protein S171
Uniprot Accession: P49757, Q9QZS3
Entrez GeneID: 18222, 395639, 8650
Gene Symbol: NUMB
The target sequence has 90% sequence homology with rat.