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Neurofilament, Medium chain Polyclonal Antibody, Invitrogen™

Neurofilament, Medium chain Antibody, PA1-10015, from Invitrogen™. Species Reactivity: Bv, Ck, Eq, Hu, Ms, Po, Rt; Applications: ELISA, ICC, IF, IHC, WB.

Brand:  Invitrogen PA110015

UNSPSC : 12352203

Code : LD

Additional Details : Weight : 0.01000kg

Product Code. 11565862

  • £311.00 / 100┬ÁL


Estimated Shipment
28-06-2017
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Specifications

Description

Like most other intermediate filament proteins (IFPs), the expression of the different neuronal IFPs is both tissue-specific and developmentally regulated. The neurofilament (NF) triplet proteins (∽70, 160, and 200 kDa) occur in both the central and peripheral nervous system and are normally restricted to neurons. The 70 kDa NF-protein can self-assemble into a filamentous structure, whereas the 160 kDa and 200 kDa NF-proteins require the presence of the 70 kDa NF-protein to co-assemble.
Host Species: Rabbit
Cross Reactivity: Bovine, Chicken, Equine, Human, Mouse, Porcine, Rat
Isotype: IgG
Immunogen: Recombinant fusion protein containing the extreme C-terminal segment of rat NF-M
Formulation: 100μL unpurified antibody in whole serum and no preservative
Synonyms: NFM, NF-M, NMC,160 kD neurofilament protein, neurofilament medium polypeptide, neurofilament 3, NEF3
Uniprot Accession: O77788, P07197, P08552, P08553, P12839, P16053
Entrez GeneID: 100054129, 100625407, 18040, 24588, 281347, 396206, 4741
Gene Symbol: NEFM
In Western blot, this antibody detects bands at ∽145kDa in crude homogenates of rat cerebellum homogenate. Human and bovine run slower at ∽160kDa. A minor band at1∽110kDa is also frequently seen, which appears to be an in-vivo proteolytic fragment of NF-M.
Description & Specifications

Specifications

Neurofilament, Medium chain
Unlabeled
O77788, P07197, P08552, P08553, P12839, P16053
NFM, NF-M, NMC,160 kD neurofilament protein, neurofilament medium polypeptide, neurofilament 3, NEF3
Rabbit
IgG
avoiding freeze/thaw cycles.
Polyclonal
Rat
Western Blot
100μL unpurified antibody in whole serum and no preservative
Serum
NEFM
Recombinant fusion protein containing the extreme C-terminal segment of rat NF-M
100μL
Primary
100054129, 100625407, 18040, 24588, 281347, 396206, 4741