anti-Neurofilament, Medium chain Polyclonal, Thermo Scientific™

Neurofilament, Medium chain Polyclonal Ab PA1-10001 detects Neurofilament, Medium chain in Bv, Ck, Eq, Hu, Ms, Po and Rt samples, and is validated for ICC, IF, IHC and WB

Overview
Brand: Invitrogen

Manufacturer Part Number: PA1-10015

NEUROFILAMENT, MEDIUM CHAIN

UNSPSC: 12352203

Code: LD

Additional Details:
Additional Details: Weight: 0.01000kg



Product Code. 11565862

Quantity Price
1 £ 311.0 / 100µL
Estimated Shipment date
from Supplier 10-01-2017
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Description and Specification

Specification

Antigen Neurofilament, Medium chain
Applications Enzyme Linked Immunosorbent Assay
Applications Immunocytochemistry
Applications Immunofluorescence
Applications Immunohistochemistry
Applications Western Blot
Conjugate Unlabeled
Cross Reactivity Bovine
Cross Reactivity Chicken
Cross Reactivity Equine
Cross Reactivity Human
Cross Reactivity Mouse
Cross Reactivity Porcine
Cross Reactivity Rat
Format Serum
Formulation 100μL unpurified antibody in whole serum and no preservative
Gene Accession No. O77788, P07197, P08552, P08553, P12839, P16053
Gene Alias NFM, NF-M, NMC,160 kD neurofilament protein, neurofilament medium polypeptide, neurofilament 3, NEF3
Gene Symbols NEFM
Host Species Rabbit
Immunogen Recombinant fusion protein containing the extreme C-terminal segment of rat NF-M
Isotype IgG
Quantity 100μL
Species Reactivity Bovine, Chicken, Equine, Human, Mouse, Porcine, Rat
Storage Requirements avoiding freeze/thaw cycles.
Primary or Secondary Primary
Monoclonal or Polyclonal Polyclonal
Gene ID (Entrez) 100054129, 100625407, 18040, 24588, 281347, 396206, 4741

Like most other intermediate filament proteins (IFPs), the expression of the different neuronal IFPs is both tissue-specific and developmentally regulated. The neurofilament (NF) triplet proteins (∽70, 160, and 200 kDa) occur in both the central and peripheral nervous system and are normally restricted to neurons. The 70 kDa NF-protein can self-assemble into a filamentous structure, whereas the 160 kDa and 200 kDa NF-proteins require the presence of the 70 kDa NF-protein to co-assemble.
Host Species: Rabbit
Cross Reactivity: Bovine, Chicken, Equine, Human, Mouse, Porcine, Rat
Isotype: IgG
Immunogen: Recombinant fusion protein containing the extreme C-terminal segment of rat NF-M
Formulation: 100μL unpurified antibody in whole serum and no preservative
Synonyms: NFM, NF-M, NMC,160 kD neurofilament protein, neurofilament medium polypeptide, neurofilament 3, NEF3
Uniprot Accession: O77788, P07197, P08552, P08553, P12839, P16053
Entrez GeneID: 100054129, 100625407, 18040, 24588, 281347, 396206, 4741
Gene Symbol: NEFM
In Western blot, this antibody detects bands at ∽145kDa in crude homogenates of rat cerebellum homogenate. Human and bovine run slower at ∽160kDa. A minor band at1∽110kDa is also frequently seen, which appears to be an in-vivo proteolytic fragment of NF-M.