missing translation for 'onlineSavingsMsg'
Learn More

Netrin 1 Polyclonal Antibody, Invitrogen™

Netrin 1 Antibody, PA1-12866, from Invitrogen™. Species Reactivity: Bovine, Feline, Human, Mouse, Non-human primate, Rat; Applications: Western Blot.

Brand:  Invitrogen PA112866

UNSPSC : 12352203

Code : LD

Additional Details : Weight : 0.01000kg

Product Code. 11570523

  • £375.00 / 25µg


Estimated Shipment
25-09-2017
Add to basket

Description

Description

Netrin 1’s main receptor is DCC (deleted in colorectal cancer- a putative tumor suppressor gene whose expression is lost in numerous cancers). DCC belongs to the so-called family of dependence receptors. These receptors induce apoptosis when their ligand is absent, thus conferring a state of cellular dependence on Netrin 1 availability. The DCC/netrin-1 duo regulates neuron survival during nervous system development. The mechanism(s) by which Netrin 1/ DCC triggers cell death are still unknown. The localization of DCC to lipid rafts appears to be a prerequisite for its proapoptotic activity.
Host Species: Rabbit
Cross Reactivity: Bovine, Feline, Human, Mouse, Non-human primate, Rat
Isotype: IgG
Immunogen: Synthetic peptide corresponding to human Netrin 1.
Formulation: 25μg purified antibody (0.094mg/mL) in PBS and 0.08% sodium azide
Synonyms: NTN1L
Uniprot Accession: O09118, O95631, Q924Z9
Entrez GeneID: 101082606, 114523, 18208, 522767, 9423
Gene Symbol: NTN1
A suggested positive control for this product is MDCKII cell lysate.
Specifications

Specifications

Netrin 1
Unlabeled
O09118, O95631, Q924Z9
NTN1L
Rabbit
IgG
Avoid Freeze/Thaw Cycles
Polyclonal
Rat
Western Blot
25μg purified antibody (0.094mg/mL) in PBS and 0.08% sodium azide
Purified
NTN1
Synthetic peptide corresponding to human Netrin 1.
25μg
Primary
101082606, 114523, 18208, 522767, 9423