NALP1 Polyclonal Antibody, Invitrogen™

Rabbit Polyclonal Antibody

Brand:  Invitrogen PA520005

Product Code. 12868022

Description

A suggested positive control is U937 cell lysate. PA5-20005 can be used with blocking peptide PEP-0308.

NALP1 is a member of the Ced-4 family of apoptosis proteins. Ced-family members contain a caspase recruitment domain (CARD) and are known to be key mediators of programmed cell death. The encoded protein contains a distinct N-terminal pyrin-like motif, which is possibly involved in protein-protein interactions. This protein interacts strongly with caspase 2 and weakly with caspase 9. Overexpression of this gene was demonstrated to induce apoptosis in cells. Multiple alternatively spliced transcript variants encoding distinct isoforms have been found for this gene, but the biological validity of some variants has not been determined.

Specifications

• Antigen: NALP1
• Classification: Polyclonal
• Conjugate: Unconjugated
• Gene: NLRP1
• Gene Alias: CARD7; caspase recruitment domain protein; caspase recruitment domain protein 7; caspase recruitment domain-containing protein 7; CIDED; CLR17.1; death effector filament-forming Ced-4-like apoptosis protein; DEFCAP; DEFCAP-L/S; DKFZp586O1822; Gm14; Gm15; KIAA0926; NAC; nacht; NACHT, leucine rich repeat and PYD (pyrin domain) containing 1; NACHT, leucine rich repeat and PYD containing 1; NACHT, LRR and PYD containing protein 1; NACHT, LRR and PYD domains-containing protein 1; NACHT, LRR and PYD domains-containing protein 1a; NACHT/LRR/pyrin domain-containing protein 1; Nalp1; Nalp1a; NLR family protein 1; NLR family pyrin domain containing 1; NLR family, pyrin domain containing 1; NLR family, pyrin domain containing 1A; Nlrp1; Nlrp1a; Nucleotide-binding domain and caspase recruitment domain; nucleotide-binding oligomerization domain, leucine rich repeat and pyrin domain containing 1; PP1044; resistant anthrax lethal toxin; SLEV1; VAMAS1
• Host Species: Rabbit
• Purification Method: Antigen affinity chromatography
• Regulatory Status: RUO
• Gene ID (Entrez): 22861
• Content And Storage: Maintain refrigerated at 2-8°C for up to 3 months. For long term storage store at -20°C
• Form: Liquid

• Applications: Immunocytochemistry, Western Blot
• Concentration: 1 mg/mL
• Formulation: PBS with 0.02% sodium azide
• Gene Accession No.: Q9C000
• Gene Symbols: NLRP1
• Immunogen: A peptide corresponding to 13 amino acids near the carboxy terminus of human NALP1.
• Quantity: 100 μg
• Primary or Secondary: Primary
• Target Species: Human
• Product Type: Antibody
• Isotype: IgG