Myelin Basic Protein Polyclonal Antibody, Invitrogen™

Myelin Basic Protein Antibody, PA1-18324, from Invitrogen™. Species Reactivity: Human, Rat; Applications: Immunohistochemistry.

Overview
Brand: Invitrogen

Manufacturer Part Number: PA1-18324

UNSPSC: 12352203

Code: LD

Additional Details:
Additional Details: Weight: 0.01000kg



Product Code. 11551992

Quantity Price
1 £ 349.0 / 100µL
Estimated Shipment date
from Supplier 26-04-2017
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Description and Specification

Specification

Formulation 100μL unpurified antibody in whole serum and no preservative
Immunogen Synthetic peptide corresponding to residues Y(68) G S L P Q K S Q R S Q D E N P V V(86) of guinea pig MBP, conjugated to KLH.
Storage Requirements Avoid Freeze/Thaw Cycles
Cross Reactivity Human
Cross Reactivity Rat
Antigen Myelin Basic Protein
Isotype IgG
Primary or Secondary Primary
Format Serum
Gene Accession No. P02686, P02688
Species Reactivity Human, Rat
Conjugate Unlabeled
Host Species Rabbit
Quantity 100μL
Monoclonal or Polyclonal Polyclonal
Gene Symbols MBP
Applications Immunohistochemistry
Gene Alias MBP
Gene ID (Entrez) 24547, 4155

Myelin is a membrane characteristic of the nervous tissue and functions as an insulator to increase the velocity of the stimuli being transmitted between a nerve cell body and its target. Myelin isolated from human and bovine nervous tissue is composed of approximately 80% lipid and 20% protein, and 30% of the protein fraction constitutes myelin basic protein. MBP is an 'intrinsically unstructured' protein with a high proportion (approximately 75%) of random coil, but postulated to have core elements of beta-sheet and alpha-helix. MBP is a major protein in CNS myelin and is expressed specifically in the nervous system.
Host Species: Rabbit
Cross Reactivity: Human, Rat
Isotype: IgG
Immunogen: Synthetic peptide corresponding to residues Y(68) G S L P Q K S Q R S Q D E N P V V(86) of guinea pig MBP, conjugated to KLH.
Formulation: 100μL unpurified antibody in whole serum and no preservative
Synonyms: MBP
Uniprot Accession: P02686, P02688
Entrez GeneID: 24547, 4155
Gene Symbol: MBP
PA1-18324 detects MBP from human and rat samples. PA1-18324 has been successfully used in immunohistochemistry staining of MBP in abnormal oligodendrocytic process and cell bodies in demyelinating areas. This antibody recognizes only areas of myelin degeneration when tested in injured spinal cord and lesioned sciatic nerve, and also stains discrete white matter in the brain of multiple system atrophy. The PA1-18324 immunogen is a synthetic peptide corresponding to residues Y(68) G S L P Q K S Q R S Q D E N P V V(86) of guinea pig MBP, conjugated to KLH. Reconstitute with 100 ul of distilled water.