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Invitrogen™ TRPML1 Polyclonal Antibody
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Product Code. 10292434
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Quantity:
100 μL
Unit Size:
100µL
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10292434 100 μL 100µL
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Product Code. 10292434 Supplier Invitrogen™ Supplier No. PA146474

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Description

Rabbit Polyclonal Antibody

The target sequence has 85% sequence homology with monkey and 78% sequence homology with bovine. Suggested positive control: mouse brain protein.

Defects in Mucolipin-1 are the cause of mucolipidosis type IV (MLIV), also known as sialolipidosis. MLIV is an autosomal recessive lysosomal storage disorder characterized by severe psychomotor retardation and ophthalmologic abnormalities, including corneal opacity, retinal degeneration and strabismus. Storage bodies of lipids and water-soluble substances are seen by electron microscopy in almost every cell type of the patients. Most patients are unable to speak or walk independently and reach a maximal developmental level of 1-2 years. All patients have constitutive achlorhydia associated with a secondary elevation of serum gastrin levels.
TRUSTED_SUSTAINABILITY

Specifications

Antigen TRPML1
Applications Western Blot
Classification Polyclonal
Concentration 1.0 mg/mL
Conjugate Unconjugated
Formulation PBS with 0.02% sodium azide
Gene MCOLN1
Gene Accession No. Q99J21, Q9GZU1
Gene Alias 2210015I05Rik; MCLN1; Mcoln1; MCOLN1 mucolipin 1; MG-2; MGC7172; ML1; ML4; MLIV; MST080; MSTP080; Mucolipidin; mucolipidosis type IV protein; mucolipin 1; mucolipin-1; Transient receptor potential channel mucolipin 1; Transient receptor potential-mucolipin 1; TRPML1; TRP-ML1; TRPM-L1
Gene Symbols MCOLN1
Host Species Rabbit
Immunogen Synthetic peptide made to a C-terminal portion of mouse Mucolipin 1 (within residues 500-580).
Purification Method Antigen affinity chromatography
Quantity 100 μL
Regulatory Status RUO
Primary or Secondary Primary
Gene ID (Entrez) 288371, 57192, 94178
Target Species Human, Mouse, Rat
Content And Storage Store at 4°C short term. For long term storage, store at -20°C, avoiding freeze/thaw cycles.
Product Type Antibody
Form Liquid
Isotype IgG
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