LXR alpha, Polyclonal, Invitrogen™

Rabbit Polyclonal Antibody

Brand:  Invitrogen PA1332

Product Code. 11587102

Description

Liver X receptors (LXRs), also known as RLD1, are oxysterol activated nuclear receptors which are involved in the regulation of genesis and metabolism of cholesterols and bile acids. LXRs form heterodimeric complexes with the retinoic acid receptors (RARs) once activated by their respective oxysterol ligands. Two known isoforms, alpha and beta, are differentially expressed; the alpha isoform predominantly expressed in liver, whereas beta isoform expression has been shown to be ubiquitous.The corresponding gene for the LXR alpha is NR1H3.

PA1-332 detects LXR alpha in mouse samples. PA1-332 has been successfully used in Western blot procedures. By Western blot, this antibody detects an ∽50kDa protein representing LXR alpha in mouse liver samples.The PA1-332 immunogen is a synthetic peptide corresponding to residues T(35) C I L R E E A R M P Q S T G(49) of mouse LXR alpha. The PA1-332 immunizing peptide (Cat. # PEP-272) is available for use in neutralization and control experiments.

Specifications

• Antigen: LXR alpha
• Classification: Polyclonal
• Conjugate: Unconjugated
• Gene Accession No.: Q9Z0Y9
• Gene Symbols: NR1H3
• Immunogen: Synthetic peptide corresponding to residues T(35) C I L R E E A R M P Q S T G(49) of mouse LXR alpha.
• Quantity: 100 μg
• Primary or Secondary: Primary
• Target Species: Mouse
• Product Type: Antibody
• Isotype: IgG

• Applications: Western Blot
• Concentration: 1mg/mL
• Gene: Nr1h3
• Gene Alias: Liver X Receptor Alpha, Oxysterols receptor LXR-alpha, Liver X receptor alpha, Nuclear orphan receptor LXR-alpha
• Host Species: Rabbit
• Purification Method: Antigen affinity chromatography
• Regulatory Status: RUO
• Gene ID (Entrez): 22259
• Content And Storage: Store at -20°C, Avoid Freeze/Thaw Cycles
• Form: Liquid