Invitrogen™ LOXL1 Polyclonal Antibody

Rabbit Polyclonal Antibody

Brand:  Invitrogen™ PA544213

Product Code. 15526402

Description

Peptide sequence: RWRQLIQWEN NGQVYSLLNS GSEYVPAGPQ RSESSSRVLL AGAPQAQQRR Sequence homology: Cow: 83%; Guinea Pig: 100%; Horse: 92%; Human: 100%; Mouse: 100%; Rabbit: 86%; Rat: 100%.

This gene encodes a member of the lysyl oxidase gene family. The prototypic member of the family is essential to the biogenesis of connective tissue, encoding an extracellular copper-dependent amine oxidase that catalyses the first step in the formation of crosslinks in collagens and elastin. A highly conserved amino acid sequence at the C-terminus end appears to be sufficient for amine oxidase activity, suggesting that each family member may retain this function. The N-terminus is poorly conserved and may impart additional roles in developmental regulation, senescence, tumor suppression, cell growth control, and chemotaxis to each member of the family.

Specifications

• Antigen: LOXL1
• Classification: Polyclonal
• Conjugate: Unconjugated
• Gene: Loxl1
• Gene Alias: cross-linking enzyme; LOL; Lox2; LOXL; LOXL1; Lysyl oxidase 2; lysyl oxidase homolog 1; lysyl oxidase like 1; lysyl oxidase-like 1; lysyl oxidase-like protein 1
• Host Species: Rabbit
• Purification Method: Affinity chromatography
• Regulatory Status: RUO
• Gene ID (Entrez): 4016
• Content And Storage: -20°C, Avoid Freeze/Thaw Cycles
• Form: Liquid

• Applications: Western Blot
• Concentration: 0.5 mg/mL
• Formulation: PBS with 2% sucrose and 0.09% sodium azide
• Gene Accession No.: Q08397
• Gene Symbols: Loxl1
• Immunogen: Synthetic peptide directed towards the N-terminal of human LOXL1 (aa 38-87).
• Quantity: 100 μL
• Primary or Secondary: Primary
• Target Species: Human
• Product Type: Antibody
• Isotype: IgG