Invitrogen™ NGAL Polyclonal Antibody

Goat Polyclonal Antibody

Brand:  Invitrogen™ PA546916

Product Code. 15507412

Description

In direct ELISAs, approximately 50% cross-reactivity with recombinant rat Lipocalin-2/NGAL is observed, approximately 10% cross-reactivity with recombinant human (rh) Lipocalin-2/NGAL is observed, and less than 5% cross-reactivity with rhLipocalin-1 is observed. Reconstitute at 0.2 mg/mL in sterile PBS.

NGAL (Neutrophil gelatinase-associated lipocalin, lipocalin 2, siderocalin and neutrophil lipocalin) is a 25 kDa glycosylated single chain monomer and member of the lipocalin family of proteins that bind and transport small lipophilic molecules. NGAL is released by activated neutrophils, can form dimers and small amounts of higher oligomers, and complexes with matrix metalloproteinase 9 (MMP-9, gelatinase B). Low level expression of NGAL in a variety of epithelia may be increased in inflammation or cancers. Expression of NGAL in the kidney is dramatically increased by ischemic or nephrotoxic kidney injury.

Specifications

• Antigen: NGAL
• Classification: Polyclonal
• Conjugate: Unconjugated
• Gene: LCN2
• Gene Alias: 24p3; 25 kDa alpha-2-microglobulin-related subunit of MMP-9; alpha-2-microglobulin-related protein; Alpha-2U globulin-related protein; AW212229; HGNC:6526; HNL; LCN2; lipocalin 2; lipocalin 2 (oncogene 24p3); Lipocalin 24p3; Lipocalin2; Lipocalin-2; migration-stimulating factor inhibitor; MSFI; neutrophil gelatinase-associated lipocalin; NGAL; oncogene 24p3; OTTHUMP00000022240; p25; RP23-161B9.11; secreted inducible protein 24; Siderocalin; Siderocalin LCN2; Sip24; SV-40-induced 24P3 protein; uterocalin
• Host Species: Goat
• Purification Method: Antigen affinity chromatography
• Regulatory Status: RUO
• Gene ID (Entrez): 16819
• Content And Storage: -20°C, Avoid Freeze/Thaw Cycles
• Form: Lyophilized

• Applications: Immunohistochemistry (Frozen), Immunoprecipitation, Western Blot
• Concentration: 0.2 mg/mL
• Formulation: PBS with 5% trehalose and No Preservative
• Gene Accession No.: P11672
• Gene Symbols: LCN2
• Immunogen: Mouse myeloma cell line NS0-derived recombinant mouse Lipocalin-2/NGAL Gln21-Asn200.
• Quantity: 100 μg
• Primary or Secondary: Primary
• Target Species: Mouse
• Product Type: Antibody
• Isotype: IgG