KRIP-1 Mouse, Unlabeled, Clone: 23, BD

Mouse Monoclonal Antibody

Brand:  BD Biosciences 610680

Product Code. 15885579

Description

Several gene regulatory proteins contain “zinc finger” domains of about 30 amino acids and N-terminal regions of about 75 amino acids, named the Krnppel-associated box A (KRAB-A). The KRAB-A domains have been implicated in transcriptional repression. KRIP-1 (KRAB-A-interacting protein 1) was identified as a result of its interaction with a KRAB-A domain. KRIP-1 is 834 amino acids with an apparent molecular weight of 105kDa. Sequence alignments indicate that KRIP-1 shares identity with TIF-1, a transcriptional regulator of nuclear receptors. The region responsible for the transcriptional activity in KRIP-1 is located in the C-terminal region, which also contains a Cys4-His-Cys3 PHD finger domain.

Immunofluorescence, Immunohistochemistry, Immunoprecipitation, Western Blotting

Specifications

• Antigen: KRIP-1
• Classification: Monoclonal
• Concentration: 250μg/mL
• Description: KRAB-A Interacting Protein-1
• Host Species: Mouse
• Purification Method: Affinity Purified
• Regulatory Status: RUO
• Primary or Secondary: Primary
• Content And Storage: Store undiluted at -20°C.

• Applications: Western Blot
• Clone: 23
• Conjugate: Unconjugated
• Formulation: Aqueous buffered solution containing BSA, glycerol, and ≤0.09% sodium azide.
• Immunogen: Aqueous buffered solution containing BSA, glycerol, and ≤0.09% sodium azide.
• Quantity: 50 μg
• Research Discipline: Cell Biology
• Target Species: Canine, Human, Mouse, Rat
• Isotype: IgG1