KLHL12 Monoclonal Antibody (2G2), Invitrogen™

Mouse Monoclonal Antibody

Brand:  Invitrogen MA515649

Product Code. 11375613

Description

MA5-15649 targets KLHL12 in indirect ELISA, WB applications and shows reactivity with Human samples. The MA5-15649 immunogen is purified recombinant fragment of human KLHL12 expressed in E. Coli. MA5-15649 detects KLHL12 which has a predicted molecular weight of approximately 63kDa.

Serves as a substrate-specific adapter for the CUL3-based ubiquitin-protein E3 ligase complex. Negatively regulates the Wnt signaling pathway via the targeted ubiquitination and subsequent proteolysis of DVL3.Tissue specificity: Highly expressed in testis and at lower levels in the submandibular salivary gland.

Specifications

• Antigen: KLHL12
• Classification: Monoclonal
• Concentration: Conc. Not Determined
• Formulation: ascites with 0.03% sodium azide
• Gene Accession No.: Q53G59
• Gene Symbols: Klhl12
• Immunogen: Purified recombinant fragment of human KLHL12 expressed in E. Coli.
• Regulatory Status: RUO
• Gene ID (Entrez): 59349
• Content And Storage: Store at 4°C short term. For long term storage, store at -20°C, avoiding freeze/thaw cycles.
• Form: Liquid

• Applications: ELISA, Western Blot
• Clone: 2G2
• Conjugate: Unconjugated
• Gene: Klhl12
• Gene Alias: C3IP1; CUL3-interacting protein 1; DKIR; DKIR homolog; FLJ27152; hDKIR; kelch like family member 12; kelch-like 12; kelch-like family member 12; kelch-like protein 12; kelch-like protein C3IP1; Klhl12; si:dkeyp-53e12.5; Unknown (protein for MGC:134560); wu:fi60g03; zgc:92570
• Host Species: Mouse
• Quantity: 100 μL
• Primary or Secondary: Primary
• Target Species: Human
• Product Type: Antibody
• Isotype: IgG1