anti-KIR2DL5A/CD158f PE, Clone: UP-R1, Invitrogen™

KIR2DL5A/CD158f Monoclonal antibody A18358 from Invitrogen specifically detects KIR2DL5A/CD158f in Human samples. It is validated for Flow Cytometry.

Brand:  Invitrogen A18358

Product Code. 15296124

Description

KIR2DL5A/CD158f Monoclonal antibody A18358 from Invitrogen specifically detects KIR2DL5A/CD158f in Human samples. It is validated for Flow Cytometry.

Killer cell immunoglobulin-like receptors (KIRs) are transmembrane glycoproteins expressed by natural killer cells and subsets of T cells. The KIR genes are polymorphic and highly homologous and they are found in a cluster on chromosome 19q13.4 within the 1 Mb leukocyte receptor complex (LRC). The gene content of the KIR gene cluster varies among haplotypes, although several “framework” genes are found in all haplotypes. The KIR proteins are classified by the number of extracellular immunoglobulin domains (2D or 3D) and by whether they have a long (L) or short (S) cytoplasmic domain. KIR proteins with the long cytoplasmic domain transduce inhibitory signals upon ligand binding via an immune tyrosine-based inhibitory motif (ITIM), while KIR proteins with the short cytoplasmic domain lack the ITIM motif and instead associate with the TYRO protein tyrosine kinase binding protein to transduce activating signals. The ligands for several KIR proteins are subsets of HLA class I molecules; thus, KIR proteins are thought to play an important role in regulation of the immune response.
Host Species: Mouse
Cross Reactivity: Human
Isotype: IgG1
Clone: UP-R1
Immunogen: human CD158f protein
Formulation: 25 Tests Purified Antibody (0.05mg/ml) in proprietary buffer, with 0.09% sodium azide
Synonyms: KIR2DL, CD158, NKAT, NKAT1
Uniprot Accession: Q8N109
Entrez GeneID: 3806
Gene Symbol: KIR2DL5A
This product detects KIR2DL5A/CD158f in Human samples. This product has been successfully used in Flow Cytometry procedures. The immunogen is human CD158f protein.

Specifications

• Antigen: KIR2DL5A/CD158f
• Classification: Monoclonal
• Conjugate: PE
• Gene Accession No.: Q8N109
• Gene Symbols: KIR2DL5A
• Immunogen: human CD158f protein
• Primary or Secondary: Primary
• Target Species: Human
• Form: Purified

• Applications: Flow Cytometry
• Clone: UP-R1
• Formulation: 25 Tests Purified Antibody (0.05mg/ml) in proprietary buffer, with 0.09% sodium azide
• Gene Alias: KIR2DL, CD158, NKAT, NKAT1
• Host Species: Mouse
• Quantity: 25 Tests
• Gene ID (Entrez): 3806
• Content And Storage: Store at 4° C
• Isotype: IgG1