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anti-KIR2DL5A/CD158f PE, Clone: UP-R1, Invitrogen™

Product Code. 15296124
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25 Tests
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15296124 25 Tests Each
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Product Code. 15296124 Supplier Invitrogen Supplier No. A18358

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Description

KIR2DL5A/CD158f Monoclonal antibody A18358 from Invitrogen specifically detects KIR2DL5A/CD158f in Human samples. It is validated for Flow Cytometry.

Killer cell immunoglobulin-like receptors (KIRs) are transmembrane glycoproteins expressed by natural killer cells and subsets of T cells. The KIR genes are polymorphic and highly homologous and they are found in a cluster on chromosome 19q13.4 within the 1 Mb leukocyte receptor complex (LRC). The gene content of the KIR gene cluster varies among haplotypes, although several “framework” genes are found in all haplotypes. The KIR proteins are classified by the number of extracellular immunoglobulin domains (2D or 3D) and by whether they have a long (L) or short (S) cytoplasmic domain. KIR proteins with the long cytoplasmic domain transduce inhibitory signals upon ligand binding via an immune tyrosine-based inhibitory motif (ITIM), while KIR proteins with the short cytoplasmic domain lack the ITIM motif and instead associate with the TYRO protein tyrosine kinase binding protein to transduce activating signals. The ligands for several KIR proteins are subsets of HLA class I molecules; thus, KIR proteins are thought to play an important role in regulation of the immune response.
Host Species: Mouse
Cross Reactivity: Human
Isotype: IgG1
Clone: UP-R1
Immunogen: human CD158f protein
Formulation: 25 Tests Purified Antibody (0.05mg/ml) in proprietary buffer, with 0.09% sodium azide
Synonyms: KIR2DL, CD158, NKAT, NKAT1
Uniprot Accession: Q8N109
Entrez GeneID: 3806
Gene Symbol: KIR2DL5A
This product detects KIR2DL5A/CD158f in Human samples. This product has been successfully used in Flow Cytometry procedures. The immunogen is human CD158f protein.
TRUSTED_SUSTAINABILITY

Specifications

Antigen KIR2DL5A/CD158f
Applications Flow Cytometry
Classification Monoclonal
Clone UP-R1
Conjugate PE
Formulation 25 Tests Purified Antibody (0.05mg/ml) in proprietary buffer, with 0.09% sodium azide
Gene Accession No. Q8N109
Gene Alias KIR2DL, CD158, NKAT, NKAT1
Gene Symbols KIR2DL5A
Host Species Mouse
Immunogen human CD158f protein
Quantity 25 Tests
Primary or Secondary Primary
Gene ID (Entrez) 3806
Target Species Human
Content And Storage Store at 4° C
Form Purified
Isotype IgG1
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