Invitrogen™ JAM2 Polyclonal Antibody

Rabbit Polyclonal Antibody

Brand:  Invitrogen™ PA521576

Product Code. 13219148

Beskrivelse

Recommended positive controls: A431, Neuro2A, GL261, C8D30, NIH-3T3, BCL-1, Raw264.7, C2C12. Predicted reactivity: Mouse (81%), Rat (81%), Bovine (90%). Store product as a concentrated solution. Centrifuge briefly prior to opening the vial.

Tight junctions represent one mode of cell-to-cell adhesion in epithelial or endothelial cell sheets, forming continuous seals around cells and serving as a physical barrier to prevent solutes and water from passing freely through the paracellular space. The protein encoded by this immunoglobulin superfamily gene member is localized in the tight junctions between high endothelial cells. It acts as an adhesive ligand for interacting with a variety of immune cell types and may play a role in lymphocyte homing to secondary lymphoid organs.

Tekniske data

• Antigen: JAM2
• Classification: Polyclonal
• Conjugate: Unconjugated
• Gene: JAM2
• Gene Alias: 1110002N23Rik; 2410030G21Rik; 2410167M24Rik; AU016127; C21orf43; CD322; Jam2; JAM-2; JAMB; JAM-B; JAM-IT/VE-JAM; Jcam2; junction adhesion molecule 2; junction adhesion molecule B; junction cell adhesion molecule 2; junctional adhesion molecule 2; Junctional adhesion molecule B; PRO245; RP23-253E17.2; UNQ219/PRO245; Vascular endothelial junction-associated molecule; VEJAM; VE-JAM
• Host Species: Rabbit
• Purification Method: Antigen affinity chromatography
• Regulatory Status: RUO
• Gene ID (Entrez): 58494
• Content And Storage: Store at 4°C short term. For long term storage, store at -20°C, avoiding freeze/thaw cycles.
• Form: Liquid

• Applications: Immunohistochemistry (Paraffin), Western Blot
• Concentration: 1 mg/mL
• Formulation: 0.1M tris glycine with 10% glycerol and 0.01% thimerosal; pH 7
• Gene Accession No.: P57087
• Gene Symbols: JAM2
• Immunogen: Recombinant protein encompassing a sequence within the center region of human JAM-B. The exact sequence is proprietary.
• Quantity: 100 μL
• Primary or Secondary: Primary
• Target Species: Human
• Product Type: Antibody
• Isotype: IgG