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Invitrogen™ IRF9 Polyclonal Antibody
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Product Code. 15584102
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Quantity:
100 μL
Unit Size:
100µL
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15584102 100 μL 100µL
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Product Code. 15584102 Supplier Invitrogen™ Supplier No. PA540357

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Description

Rabbit Polyclonal Antibody

Peptide sequence: PWKHAGKQDF REDQDAAFFK AWAIFKGKYK EGDTGGPAVW KTRLRCALNK Sequence homology: Cow: 100%; Dog: 100%; Guinea Pig: 100%; Horse: 100%; Human: 100%; Mouse: 100%; Rabbit: 100%; Rat: 100%; Zebrafish: 79%.

Transcription factor that plays an essential role in anti-viral immunity. It mediates signaling by type I IFNs (IFN-alpha and IFN-beta). Following type I IFN binding to cell surface receptors, Jak kinases (TYK2 and JAK1) are activated, leading to tyrosine phosphorylation of STAT1 and STAT2. IRF9/ISGF3G associates with the phosphorylated STAT1:STAT2 dimer to form a complex termed ISGF3 transcription factor, that enters the nucleus. ISGF3 binds to the IFN stimulated response element (ISRE) to activate the transcription of interferon stimulated genes, which drive the cell in an antiviral state. [UniProt].
TRUSTED_SUSTAINABILITY

Specifications

Antigen IRF9
Applications Immunohistochemistry, Western Blot, Surface Plasmon Resonance
Classification Polyclonal
Concentration 0.5 mg/mL
Conjugate Unconjugated
Formulation PBS with 2% sucrose and 0.09% sodium azide
Gene IRF9
Gene Accession No. Q00978
Gene Alias gamma 48kDa; IFN alpha responsive transcription factor subunit; IFN-alpha-responsive transcription factor subunit; interferon dependent positive acting transcription factor 3 gamma; interferon regulatory factor 9; Interferon-stimulated gene factor 3 gamma; interferon-stimulated transcription factor 3; interferon-stimulated transcription factor 3, gamma (48kD); interferon-stimulated transcription factor 3, gamma 48kDa; IRF9; Irf-9; ISGF3; ISGF-3 gamma; ISGF3 p48 subunit; ISGF3G; p48; transcriptional regulator ISGF3 subunit gamma; Unknown (protein for MGC:126912); Unknown (protein for MGC:92097); zgc:92097
Gene Symbols IRF9
Host Species Rabbit
Immunogen Synthetic peptide directed towards the N-terminal of human ISGF3G (aa 41-90).
Purification Method Affinity Chromatography
Quantity 100 μL
Regulatory Status RUO
Primary or Secondary Primary
Gene ID (Entrez) 10379
Target Species Human
Content And Storage -20°C, Avoid Freeze/Thaw Cycles
Product Type Antibody
Form Liquid
Isotype IgG
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