Intersectin/ESE-1 Mouse, Unlabeled, Clone: 29, BD

Mouse Monoclonal Antibody

Brand:  BD Biosciences 611574

Product Code. 15875979

Description

ESE-1 (epithelium-specific, EH domain and SH3 domain regulator of endocytosis) contains two N-terminal EH (Ep15 homology) domains, a central coiled-coil domain, and five C-terminal SH3 domains. ESE-1 is also known as the adaptor protein Intersectin. Intersectin constitutively associates with Eps15 to form a complex that is analogous to the yeast Pan1p-End3p complex, which is required for endocytosis and organization of the actin cytoskeleton. The EH, coiled-coil, and SH3 domains of intersectin bind epsin family proteins, SNAP25 and SNAP23, and dynamin, respectively. Thus, intersectin functions in complex with Eps15 to regulate endocytosis by linking components of the endocytic machinery.

Host Species: Mouse
Clone: 29
Isotype: IgG1
Species Reactivity: Rat
Immunogen: Mouse Ese-1 aa. 800-909
Formula Weight [Chemical]: 140/200kDa

Immunofluorescence, Western Blotting

Specifications

• Antigen: Intersectin/ESE-1
• Classification: Monoclonal
• Concentration: 250μg/mL
• Formulation: Aqueous buffered solution containing BSA, glycerol, and ≤0.09% sodium azide.
• Immunogen: Mouse Ese-1 aa. 800-909
• Quantity: 50 μg
• Research Discipline: Cell Biology
• Target Species: Chicken, Mouse, Rat
• Isotype: IgG1

• Applications: Western Blot
• Clone: 29
• Conjugate: Unconjugated
• Host Species: Mouse
• Purification Method: Affinity Purified
• Regulatory Status: RUO
• Primary or Secondary: Primary
• Content And Storage: Store undiluted at -20°C.