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  6. 11544402

anti-Insulin Receptor, Clone: MA-20, Invitrogen™

Specifically detect CD220 / Insulin Receptor in Human samples using Thermo Scientifc™ Pierce™ anti-CD220 / Insulin Receptor Clone: MA-20, validated for BLOCK, Neu and WB

Brand:  Thermo Scientific MA1-16812

Product Code. 11544402

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Description

Description

Specifically detect CD220 / Insulin Receptor in Human samples using Thermo Scientifc™ Pierce™ anti-CD220 / Insulin Receptor Clone: MA-20, validated for BLOCK, Neu and WB

The insulin receptor is functionally important for negative cooperativity, down-regulation, and beta-subunit tyrosine kinase activity. There are two recognized epitopes of the alpha-subunit. One epitope is close to the insulin-binding site and plays a role in insulin-induced negative cooperativity and down-regulation. The other site (recognized by the monoclonal MA-20 antibody) is at a distance from the insulin-binding site, where it only plays a role in down-regulation. Both epitopes appear to be independent of insulin receptor tyrosine kinase activity.

Host Species: Mouse

Cross Reactivity: Human

Isotype: IgG2b

Clone: MA-20

Immunogen: Highly purified insulin receptors (alpha-subunit) from human term placentas.

Formulation: 100μL of Protein G purified antibody (1.2mg/mL) in PBS buffer; pH 7.4.

Uniprot Accession: P06213

Gene Symbol: INSR

Entrez Gene ID: 3643, 24954

MA1-16812 detects CD220 / Insulin Receptor in Human samples. MA1-16812 has been successfully used in BLOCK, Neu and WB procedures.MA1-16812 The immunogen is Highly purified insulin receptors (alpha-subunit) from human term placentas.

TRUSTED_SUSTAINABILITY
Specifications

Specifications

Insulin Receptor
Monoclonal
Unconjugated
Mouse
100 μL
Primary
Store at -20°C. Avoid freeze/Thaw cycles.
IgG2b
ELISA, Immunoprecipitation
MA-20
INSR
Highly purified insulin receptors (alpha-subunit) from human term placentas.
RUO
Human
Purified
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