Invitrogen™ ING5 Polyclonal Antibody

Rabbit Polyclonal Antibody

Brand:  Invitrogen™ PA521443

Product Code. 13288878

Description

Recommended positive controls: Jurkat. Predicted reactivity: Mouse (100%), Rat (100%), Xenopus laevis (100%), Chicken (100%), Rhesus Monkey (100%), Bovine (100%). Store product as a concentrated solution. Centrifuge briefly prior to opening the vial.

ING5 is similar to ING1, a tumor suppressor protein that can interact with TP53, inhibit cell growth, and induce apoptosis. This protein contains a PHD-finger, which is a common motif in proteins involved in chromatin remodeling. This protein can bind TP53 and EP300/p300, a component of the histone acetyl transferase complex, suggesting its involvement in TP53-dependent regulatory pathway.

Specifications

• Antigen: ING5
• Classification: Polyclonal
• Conjugate: Unconjugated
• Gene: ING5
• Gene Alias: 1700001C14Rik; 1700027H23Rik; 1810018M11Rik; AI225768; ING5; inhibitor of growth family member 5; inhibitor of growth family, member 5; inhibitor of growth protein 5; p28ING5
• Host Species: Rabbit
• Purification Method: Antigen affinity chromatography
• Regulatory Status: RUO
• Gene ID (Entrez): 84289
• Content And Storage: Store at 4°C short term. For long term storage, store at -20°C, avoiding freeze/thaw cycles.
• Form: Liquid

• Applications: Western Blot
• Concentration: 1 mg/mL
• Formulation: PBS with 40% glycerol and 0.01% thimerosal; pH 7
• Gene Accession No.: Q8WYH8
• Gene Symbols: ING5
• Immunogen: Carrier-protein conjugated synthetic peptide encompassing a sequence within the center region of human ING5. The exact sequence is proprietary.
• Quantity: 100 μL
• Primary or Secondary: Primary
• Target Species: Human
• Product Type: Antibody
• Isotype: IgG