IL-17A Rat anti-Mouse, Alexa Fluor 488, Clone: TC11-18H10, BD

Rat Monoclonal Antibody

Product Code	Brand	Quantity
15820029	BD Biosciences 560221	25 μg
15810029	BD Biosciences 560220	0.1 mg

Description

The TC11-18H10 antibody reacts with recombinant and natural mouse IL-17A proteins. IL-17A, also known as CTLA-8, is a T cell-derived cytokine that promotes inflammatory responses. Mouse IL-17A is a proinflammatory cytokine that can induce the release of IL-6 by mouse stromal cells. It has been shown to support the growth of hemopoietic progenitors in vitro; it can also stimulate granulopoiesis in vivo. The TC11-18H10 antibody has been reported to neutralize IL-17A activity. Recent studies have shown that IL-17A is produced by a unique subset of Th17 cells that develop along a pathway distinct from the Th1- and Th2- cell differentiation pathways. The mouse IL-17A cDNA was isolated from a cDNA library generated from TCRαβ+CD4-CD8-thymocytes.

Host Species: Rat
Clone: TC11-18H10
Isotype: IgG1 κ
Species Reactivity: Mouse
Immunogen: Recombinant Mouse IL-17A Protein

Intracellular Staining

Specifications

• Antigen: IL-17A
• Concentration: 0.2mg/mL
• Classification: Monoclonal
• Host Species: Rat
• Research Discipline: Immunology
• Formulation: Aqueous buffered solution containing ≤0.09% sodium azide.
• Primary or Secondary: Primary
• Content And Storage: Store undiluted at 4°C and protected from prolonged exposure to light. Do not freeze.

• Clone: TC11-18H10
• Applications: Flow Cytometry
• Conjugate: Alexa Fluor 488
• Regulatory Status: RUO
• Target Species: Mouse
• Isotype: IgG1 κ
• Purification Method: Affinity Purified

For Research Use Only.