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HSPBAP1 Polyclonal Antibody, Invitrogen™
Rabbit Polyclonal Antibody
Brand: Invitrogen PA530818
This item is not returnable.
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Description
Recommended positive controls: 293T, A431, Jurkat, Raji. Predicted reactivity: Chimpanzee (99%). Store product as a concentrated solution. Centrifuge briefly prior to opening the vial.
HSPBAP1 (HSPB (heat shock 27kDa) associated protein 1), also known as PASS1 (protein associated with small stress protein 1), is a 488 amino acid cytoplasmic protein that contains one JMJC (Jumonji C) domain and shares 80% identity with its rat homolog, PASS1. Widely expressed with highest expression in ovary, thymus and pancreas, HSPBAP1 is thought to play a role in mediating cellular stress responses within the cell. Due to the presence of a JMJC domain, HSPBAP1 may be involved in chromatin remodeling events. Defects or translocations in the gene encoding HSPBAP1 are associated with renal cell carcinoma 1 (RCC1), suggesting a possible role for HSPBAP1 in carcinogenesis. Three isoforms of HSPBAP1 exist due to alternative splicing events.Specifications
HSPBAP1 | |
Polyclonal | |
Unconjugated | |
HSPBAP1 | |
27 kDa heat shock protein-associated protein 1; 3830421G21Rik; FLJ22623; FLJ39386; Heat shock protein; HSP; HSP27; HSP28; HSPB (heat shock 27kDa) associated protein 1; Hspb associated protein 1; HSPB1 associated protein 1; HSPB1-associated protein 1; HSPBAP1; PASS1; protein associated with small stress protein 1; protein associating with small stress protein PASS1 | |
Rabbit | |
Antigen affinity chromatography | |
RUO | |
79663 | |
Store at 4°C short term. For long term storage, store at -20°C, avoiding freeze/thaw cycles. | |
Liquid |
Western Blot | |
0.92 mg/mL | |
PBS with 1% BSA, 20% glycerol and 0.01% thimerosal; pH 7 | |
Q96EW2 | |
HSPBAP1 | |
Recombinant fragment corresponding to a region within amino acids 233 and 456 of Human HSPBAP1 | |
100 μL | |
Primary | |
Human | |
Antibody | |
IgG |