PDCD2 Monoclonal Antibody (DHIC2-5H10), Invitrogen™

Mouse Monoclonal Antibody

Brand:  Invitrogen MA516135

Product Code. 13277588

Description

Essential component of an SCF-type E3 ligase complex, SCF(NIPA), a complex that controls mitotic entry by mediating ubiquitination and subsequent degradation of cyclin B1 (CCNB1). Its cell-cycle-dependent phosphorylation regulates the assembly of the SCF(NIPA) complex, restricting CCNB1 ubiquitination activity to interphase. Its inactivation results in nuclear accumulation of CCNB1 in interphase and premature mitotic entry. May have an antiapoptotic role in NPM-ALK-mediated signaling events.

Specifications

• Antigen: PDCD2
• Classification: Monoclonal
• Concentration: Conc. Not Determined
• Formulation: tissue culture supernatant with 0.05% sodium azide
• Gene Accession No.: Q16342
• Gene Symbols: Pdcd2
• Immunogen: Human pancreatic enriched duct cells
• Regulatory Status: RUO
• Gene ID (Entrez): 5134
• Content And Storage: 4° C, do not freeze
• Form: Liquid

• Applications: Flow Cytometry, Immunocytochemistry, Immunohistochemistry (Frozen)
• Clone: DHIC2-5H10
• Conjugate: Unconjugated
• Gene: Pdcd2
• Gene Alias: AI528543; hypothetical protein MGC63685; Pcd2; PDCD2; programmed cell death 2; programmed cell death protein 2; RP8; RP-8; zgc:63685; zinc finger MYND domain-containing protein 7; Zinc finger protein Rp-8; ZMYND7
• Host Species: Mouse
• Quantity: 100 μL
• Primary or Secondary: Primary
• Target Species: Human
• Product Type: Antibody
• Isotype: IgM