hnRNP L Rabbit anti-Human, Polyclonal, Invitrogen™

Rabbit Polyclonal Antibody

Brand:  Invitrogen PA519735

Product Code. 11317683

Description

This antibody is predicted to react with mouse and Xenopus laevis based on sequence homology.

Heterogeneous nuclear RNAs which include mRNA precursors and mature mRNAs are associated with specific proteins to form heterogenous ribonucleoprotein complexes. Heterogeneous nuclear ribonucleoprotein L is among the proteins that are stably associated with hnRNP complexes and along with other hnRNP proteins is likely to play a major role in the formation, packaging, processing, and function of mRNA. Heterogeneous nuclear ribonucleoprotein L is present in the nucleoplasm as part of the HNRP complex. HNRP proteins have also been identified outside of the nucleoplasm. Exchange of hnRNP for mRNA-binding proteins accompanies transport of mRNA from the nucleus to the cytoplasm. Since HNRP proteins have been shown to shuttle between the nucleus and the cytoplasm, it is possible that they also have cytoplasmic functions. Two transcript variants encoding different isoforms have been found for this gene.

Specifications

• Antigen: hnRNP L
• Classification: Polyclonal
• Conjugate: Unconjugated
• Gene Accession No.: P14866
• Gene Symbols: HNRNPL
• Immunogen: Synthetic peptide conjugated to KLH derived from within residues 50 - 150 of Human hnRNP L.
• Quantity: 100 μg
• Primary or Secondary: Primary
• Target Species: Human
• Product Type: Antibody
• Isotype: IgG

• Applications: Immunocytochemistry, Immunofluorescence, Western Blot
• Concentration: 1 mg/mL
• Gene: HNRNPL
• Gene Alias: P/OKcl.14, FLJ35509, HNRPL, hnRNP-L, hnRNP L
• Host Species: Rabbit
• Purification Method: Antigen affinity chromatography
• Regulatory Status: RUO
• Gene ID (Entrez): 3191
• Content And Storage: Store at 4°C short term. For long term storage, store at -20°C, avoiding freeze/thaw cycles.
• Form: Liquid