hnRNP H1 Polyclonal Antibody, Invitrogen™

Rabbit Polyclonal Antibody

Brand:  Invitrogen PA527610

Product Code. 13471737

Description

Recommended positive controls: A431, H1299, HeLa, HepG2, Raji, NCI-H929, mouse brain. Predicted reactivity: Mouse (100%), Rat (99%), Zebrafish (87%), Xenopus laevis (91%), Chicken (96%), Bovine (100%). Store product as a concentrated solution. Centrifuge briefly prior to opening the vial.

This gene encodes a member of a subfamily of ubiquitously expressed heterogeneous nuclear ribonucleoproteins (hnRNPs). The hnRNPs are RNA binding proteins that complex with heterogeneous nuclear RNA. These proteins are associated with pre-mRNAs in the nucleus and appear to influence pre-mRNA processing and other aspects of mRNA metabolism and transport. While all of the hnRNPs are present in the nucleus, some may shuttle between the nucleus and the cytoplasm. The hnRNP proteins have distinct nucleic acid binding properties. The protein encoded by this gene has three repeats of quasi-RRM domains that bind to RNA and is very similar to the family member HNRPF. This gene may be associated with hereditary lymphedema type I. Alternatively spliced transcript variants have been described.

Specifications

• Antigen: hnRNP H1
• Classification: Polyclonal
• Conjugate: Unconjugated
• Gene: Hnrnph1
• Gene Alias: AI642080; E430005G16Rik; Heterogeneous nuclear ribonucleoprotein H; Heterogeneous nuclear ribonucleoprotein H, N-terminally processed; heterogeneous nuclear ribonucleoprotein H1; heterogeneous nuclear ribonucleoprotein H1 (H); hnRNP H; Hnrnph; HNRNPH1; HNRPH; HNRPH1; Ratsg1
• Host Species: Rabbit
• Purification Method: Antigen affinity chromatography
• Regulatory Status: RUO
• Gene ID (Entrez): 3187, 59013
• Content And Storage: Store at 4°C short term. For long term storage, store at -20°C, avoiding freeze/thaw cycles.
• Form: Liquid

• Applications: Immunocytochemistry, Immunohistochemistry (Paraffin), Western Blot
• Concentration: 1 mg/mL
• Formulation: 0.1M tris glycine with 10% glycerol and 0.01% thimerosal; pH 7
• Gene Accession No.: O35737, P31943
• Gene Symbols: Hnrnph1
• Immunogen: Recombinant fragment corresponding to a region within amino acids 50 and 289 of Human hnRNP H
• Quantity: 100 μL
• Primary or Secondary: Primary
• Target Species: Human, Mouse
• Product Type: Antibody
• Isotype: IgG