Granulysin Mouse anti-Human, Alexa Fluor 488, Clone: RB1, BD

Mouse Monoclonal Antibody

Brand:  BD Biosciences 558254

Product Code. 15869258

Description

The monoclonal antibody RB1 recognizes both 15- and 9kDa forms of human granulysin, a protein present in granules of human natural killer (NK) cells and activated cytotoxix T lymphocytes (CTLs). It is cytolytic against both tumor and microbial targets and has been found to kill extracellular and intracellular mycobacterium tuberculosis through a granule-dependent mechanism. Granulysin is a member of a larger family of proteins known as saposin-like proteins (SAPLIP) that are thought to associate with lipids. The crystal structure of granulysin suggests that it functions as a lytic molecule. To date, no granulysin homolog has been found in mice, precluding the generation of granulysin knockout animals.

Specifications

• Antigen: Granulysin
• Classification: Monoclonal
• Conjugate: Alexa Fluor 488
• Host Species: Mouse
• Quantity: 100 Tests
• Research Discipline: Immunology
• Target Species: Human
• Isotype: IgG1 κ

• Applications: Flow Cytometry
• Clone: RB1
• Formulation: Aqueous buffered solution containing BSA and ≤0.09% sodium azide.
• Purification Method: Affinity Purified
• Regulatory Status: RUO
• Primary or Secondary: Primary
• Content And Storage: Store undiluted at 4°C and protected from prolonged exposure to light. Do not freeze.

For Research Use Only.