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GPX4 Polyclonal Antibody, Invitrogen™
Rabbit Polyclonal Antibody
Brand: Invitrogen PA519695
This item is not returnable.
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Description
This antibody is predicted to react with many species based on sequence homology.
Glutathione peroxidase catalyzes the reduction of hydrogen peroxide, organic hydroperoxide, and lipid peroxides by reduced glutathione and functions in the protection of cells against oxidative damage. Human plasma glutathione peroxidase has been shown to be a selenium-containing enzyme and the UGA codon is translated into a selenocysteine. Through alternative splicing and transcription initiation, rat produces proteins that localize to the nucleus, mitochondrion, and cytoplasm. In humans, experimental evidence for alternative splicing exists; alternative transcription initiation and the cleavage sites of the mitochondrial and nuclear transit peptides need to be experimentally verified.
Specifications
| GPX4 | |
| Polyclonal | |
| Unconjugated | |
| GPX4 | |
| glutathione peroxidase 4; GP-GPx4; Gpx4; gpx-4; GSHPx-4; HGNC:4556; MCSP; mtPHGPx; Phgpx; phospholipid hydroperoxidase; phospholipid hydroperoxide glutathione peroxidase; phospholipid hydroperoxide glutathione peroxidase, mitochondrial; phospholipid hydroperoxide glutathione peroxidase, nuclear; SMDS; snGPx; snPHGPx; sperm nuclei glutathione peroxidase; sperm nucleus glutathione peroxidase | |
| Rabbit | |
| Antigen affinity chromatography | |
| RUO | |
| 2879 | |
| Store at 4°C short term. For long term storage, store at -20°C, avoiding freeze/thaw cycles. | |
| Liquid |
| Immunocytochemistry, Western Blot | |
| 1 mg/mL | |
| PBS with 1% BSA and 0.02% sodium azide; pH 7.4 | |
| P36969 | |
| GPX4 | |
| Synthetic peptide conjugated to KLH derived from within residues 50 - 150 of Human Glutathione Peroxidase 4. | |
| 100 μg | |
| Primary | |
| Human | |
| Antibody | |
| IgG |