GC Mouse anti-Human, Biotin, Clone: 2G2, Invitrogen™

Mouse Monoclonal Antibody

Brand:  Invitrogen HYB24901B005

Product Code. 10128413

Description

HYB 249-01B-005 detects Gc-Globulin in human samples. HYB 249-01B-005 is suggested for use in ELISA and Western blotting techniques. HYB 249-01B-005 reacts strongly with Gc-globulin. Strong reaction is seen in ELISA with Gc-globulin coated directly onto the microtiter well and when tested in sandwich ELISA in combination with a polyclonal antibody against Gc-globulin. In Western blotting after SDS-PAGE, HYB 249-01B-005 reacts with Gc-globulin in both reduced as well as unreduced forms. The HYB 249-01B-005 immunogen is Gc-Globulin isolated from human plasma. NOTE: Concentration is lot-dependent and can vary from 0.85-1.15 mg/mL

GC (vitamin D-binding protein) is involved in vitamin D transport/storage, scavenging of extracellular G-actin, enhancement of the chemotactic activity of C5 alpha for neutrophils in inflammation and macrophage activation.

Abbreviations: AP=Affinity Purification, ChIP=Chromatin IP, CM=Confocal Microscopy, DB=Dot Blot, EIA=ELISA, EM=Electron Microscopy, FC=Flow Cytometry, GS=Gel Supershift, IC=Immunocytochemistry, IF=Immunofluorescence, IH=Immunohistology/Immunohistochemistry, IP=Immunoprecipitation, IPK=IP Kinase Assay, KA=Kinase Assay, NEUT=Neutralization, PIA=Peptide Inhibition Assay, RIA=Radioimmunossay, TCA=T Cell Activation, WB=Western Blotting, Species: Am=Amphibian, Av=Avian, B=Bovine, Ca=Cat ,Ck=Chicken, D=Dog, Dr=Deer, Ds=Drosophila, El=Elk, Fg=Frog, Fs=Fish, Ft=Ferret, G=Goat, Gp=Guinea Pig, H=Horse, Hm=Hamster, Hu=Human, K=Kangaroo, Ms=Mouse, Nhp=Non-Human Primate, O=Ovine, P=Porcine, Rb=Rabbit, Rp=Reptile, Rt=Rat, Ys=Yeast, Xn=Xenopus, (wk)=cross reacts weakly

Order Info

Not available to AH Diagnostics. KITs not available outside U.S.

Specifications

• Antigen: GC
• Classification: Monoclonal
• Concentration: 1.10 mg/mL
• Formulation: PBS with 15mM sodium azide; pH 7.4
• Gene Accession No.: P02774
• Gene Symbols: GC
• Immunogen: Gc-globulin isolated from human plasma.
• Quantity: 50 μL
• Primary or Secondary: Primary
• Target Species: Human
• Product Type: Antibody
• Isotype: IgG1

• Applications: ELISA
• Clone: 2G2
• Conjugate: Biotin
• Gene: GC
• Gene Alias: DBP, DBP/GC, GRD3, VDBG, VDBP
• Host Species: Mouse
• Purification Method: Purified
• Regulatory Status: RUO
• Gene ID (Entrez): 2638
• Content And Storage: 4° C, store in dark, DO NOT FREEZE!
• Form: Liquid