Invitrogen™ GABARAP Polyclonal Antibody

Rabbit Polyclonal Antibody

Brand:  Invitrogen™ PA118289

Product Code. 11511962

Description

Reconstitute in 100 μL of sterile water. Centrifuge to remove any insoluble material. After reconstitution keep aliquots at -20 °C for a higher stability, and at 4 °C with an appropriate antibacterial agent. Glycerol (1:1) may be added for an additional stability. Avoid repetitive freeze/thaw cycles.

Gamma-aminobutyric acid (GABA) is the main inhibitory transmitter by increasing a Cl-conductance that inhibits neuronal firing in the central nervous system. It has been shown to activate both ionotropic (GABAA) and metabotropic (GABAB) receptors as well as a third class of receptors called GABAC. GABARAP (GABAA receptor-associated protein) links GABAA receptors to the cytoskeleton and may play a role in intracellular transport of GABAA receptors and its interaction with the cytoskeleton. GABARAP belongs to the MAP1 or ATG8 like family and recent studies show that MAPK15/ERK8 is acting through interaction with ATG8 family proteins to regulate autophagy.

Specifications

• Antigen: GABARAP
• Classification: Polyclonal
• Conjugate: Unconjugated
• Gene: GABARAP
• Gene Alias: ATG8A; FLC3B; FLJ25768; GABA type A receptor-associated protein; GABA(A) receptor-associated protein; GABA-A receptor-associated protein; Gabarap; GABARAP a; GABARAP-a; gamma-aminobutyric acid receptor associated protein; gamma-aminobutyric acid receptor-associated protein; gamma-aminobutyric acid reseptor associated protein; HT004; hypothetical protein; MGC120154; MGC120155; MM46
• Host Species: Rabbit
• Quantity: 100 μL
• Primary or Secondary: Primary
• Target Species: Human, Rat
• Product Type: Antibody
• Isotype: IgG

• Applications: Immunohistochemistry (Frozen), Western Blot
• Concentration: Conc. Not Determined
• Formulation: Whole serum with no preservative
• Gene Accession No.: O95166, P60517
• Gene Symbols: GABARAP
• Immunogen: Synthetic peptide corresponding to the N-terminal residues of human GABARAP.
• Regulatory Status: RUO
• Gene ID (Entrez): 11337, 58974
• Content And Storage: -20°C, Avoid Freeze/Thaw Cycles
• Form: Lyophilized