FOXP2 Rabbit anti-Human, Mouse, Polyclonal, Invitrogen™

Rabbit Polyclonal Antibody

Brand:  Invitrogen PA525656

Product Code. 13272499

Description

This antibody is predicted to react with rat based on sequence homology.

FOXP2 is a member of the forkhead/winged-helix (FOX) family of transcription factors. It is expressed in fetal and adult brain as well as in several other organs such as the lung and gut. The protein product contains a FOX DNA-binding domain and a large polyglutamine tract and is an evolutionarily conserved transcription factor, which may bind directly to approximately 300 to 400 gene promoters in the human genome to regulate the expression of a variety of genes. This gene is required for proper development of speech and language regions of the brain during embryogenesis, and may be involved in a variety of biological pathways and cascades that may ultimately influence language development. Mutations in this gene cause speech-language disorder 1 (SPCH1), also known as autosomal domit speech and language disorder with orofacial dyspraxia. Multiple alternative transcripts encoding different isoforms have been identified in this gene.

Specifications

• Antigen: FOXP2
• Classification: Polyclonal
• Gene: FOXP2
• Gene Alias: CAGH44, SPCH1, TNRC10, CAG repeat protein 44, forkhead box protein P2, forkhead/winged-helix transcription factor, trinucleotide repeat containing 10, trinucleotide repeat-containing gene 10 protein
• Host Species: Rabbit
• Purification Method: Antigen affinity chromatography
• Regulatory Status: RUO
• Gene ID (Entrez): 114142, 93986
• Content And Storage: -20° C, Avoid Freeze/Thaw Cycles
• Form: Liquid

• Applications: Immunocytochemistry, Immunofluorescence, Western Blot
• Conjugate: Unconjugated
• Gene Accession No.: O15409, P58463
• Gene Symbols: FOXP2
• Immunogen: KLH conjugated synthetic peptide between 657-684 amino acids from the C-terminal region of human FOXP2
• Quantity: 400 μL
• Primary or Secondary: Primary
• Target Species: Human, Mouse
• Product Type: Antibody
• Isotype: IgG