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FOXP2 Rabbit anti-Human, Mouse, Polyclonal, Invitrogen™

Product Code. 13272499
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Quantity:
400 μL
Unit Size:
100µg
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13272499 400 μL 100µg
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Product Code. 13272499 Supplier Invitrogen Supplier No. PA525656

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Description

Rabbit Polyclonal Antibody

This antibody is predicted to react with rat based on sequence homology.

FOXP2 is a member of the forkhead/winged-helix (FOX) family of transcription factors. It is expressed in fetal and adult brain as well as in several other organs such as the lung and gut. The protein product contains a FOX DNA-binding domain and a large polyglutamine tract and is an evolutionarily conserved transcription factor, which may bind directly to approximately 300 to 400 gene promoters in the human genome to regulate the expression of a variety of genes. This gene is required for proper development of speech and language regions of the brain during embryogenesis, and may be involved in a variety of biological pathways and cascades that may ultimately influence language development. Mutations in this gene cause speech-language disorder 1 (SPCH1), also known as autosomal domit speech and language disorder with orofacial dyspraxia. Multiple alternative transcripts encoding different isoforms have been identified in this gene.
TRUSTED_SUSTAINABILITY

Specifications

Antigen FOXP2
Applications Immunocytochemistry, Immunofluorescence, Western Blot
Classification Polyclonal
Conjugate Unconjugated
Gene FOXP2
Gene Accession No. O15409, P58463
Gene Alias CAGH44, SPCH1, TNRC10, CAG repeat protein 44, forkhead box protein P2, forkhead/winged-helix transcription factor, trinucleotide repeat containing 10, trinucleotide repeat-containing gene 10 protein
Gene Symbols FOXP2
Host Species Rabbit
Immunogen KLH conjugated synthetic peptide between 657-684 amino acids from the C-terminal region of human FOXP2
Purification Method Antigen affinity chromatography
Quantity 400 μL
Regulatory Status RUO
Primary or Secondary Primary
Gene ID (Entrez) 114142, 93986
Target Species Human, Mouse
Content And Storage -20° C, Avoid Freeze/Thaw Cycles
Product Type Antibody
Form Liquid
Isotype IgG
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